![Western Blot: FOLR2 Antibody (CL10) [NBP2-81079] - Mouse heart (lane 1), mouse lung (lane 2), mouse pancreas (lane 3), mouse testis (lane 4) and rat ovary (lane 5) samples were resolved on a 12% SDS PAGE gel and blots probed with NBP2-81079 at 1.5 ug/ml before being detected by a secondary antibody. Bands corresponding to the expected 29 kDa folate receptor protein as well as dimers thereof were detected.](http://images.novusbio.com/fullsize/FOLR2-Antibody-CL10-Western-Blot-NBP2-81079-img0001.jpg "Western Blot: FOLR2 Antibody (CL10) [NBP2-81079] - Mouse heart (lane 1), mouse lung (lane 2), mouse pancreas (lane 3), mouse testis (lane 4) and rat ovary (lane 5) samples were resolved on a 12% SDS PAGE gel and blots probed with NBP2-81079 at 1.5 ug/ml before being detected by a secondary antibody. Bands corresponding to the expected 29 kDa folate receptor protein as well as dimers thereof were detected.")
| Reactivity | MuSpecies Glossary |
| Applications | WB, IHC |
| Clone | CL10 |
| Clonality | Monoclonal |
| Host | Rat |
| Conjugate | Unconjugated |
| Format | Azide and BSA Free |
| Concentration | 1 mg/ml |
| Additional Information | Recombinant Monoclonal Antibody |
| Immunogen | FRbeta -transfected RBL2H3 cells. |
| Isotype | IgG2a Kappa |
| Clonality | Monoclonal |
| Host | Rat |
| Gene | FOLR2 |
| Purity | Protein A purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Dilutions |
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| Application Notes | The antibody binds specifically to FRbeta, a member of the folate receptor family. The receptor binds with high affinity to folic acid and folic acid derivatives, and transports 5-methyltetrahydrofolate into the cell. The receptor is expressed on the surface of tumour associated macrophages (TAMs) that promote growth and metastasis of tumours such as gliomas and colon, breast and lung carcinomas. Research has shown FRbeta is only expressed on activated macrophages, and thereby a monoclonal antibody that targets the receptor can be useful in the diagnosis of the cancer. Furthermore, the antibody may be conjugated with a toxin, delivering the drug only to TAMs and not to healthy macrophages. |
| Storage | Store at 4C for up to 3 months. For longer storage, aliquot and store at -20C. |
| Buffer | PBS |
| Preservative | 0.02% Proclin 300 |
| Concentration | 1 mg/ml |
| Purity | Protein A purified |
![Flow Cytometry FOLR1 Antibody (548908) [Unconjugated]](https://images.novusbio.com/images2/FOLR1_MAB5646_Flow_Cytometry_10781.jpg)
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Secondary Antibodies |
Isotype Controls |
Research Areas for FOLR2 Antibody (NBP2-81079)Find related products by research area.
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| Gene Symbol | FOLR2 |
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