Home » FCRN/FCGRT » FCRN/FCGRT Antibodies » FCRN/FCGRT Antibody (rozanolixizumab) - Humanized, IgG4SP

FCRN/FCGRT Antibody (rozanolixizumab) - Humanized, IgG4SP

 Submit a Review

Images

 
(
Enlarge)
Immobilized FcRn (FCGRT) His+FcRn (B2M) at 2 ug/mL can bind FCRN/FCGRT Antibody (rozanolixizumab) - Humanized, IgG4SP, EC50=0.0103 ug/mL.
Immobilized FcRn (FCGRT) His+FcRn (B2M) at 2 ug/mL can bind FCRN/FCGRT Antibody (rozanolixizumab) - Humanized, IgG4SP, EC50=0.0103 ug/mL.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, Func
Clone
rozanolixizumab
Clonality
Monoclonal
Host
Human
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-28355AF350
Alexa Fluor 405
NBP3-28355AF405
Alexa Fluor 488
NBP3-28355AF488
Alexa Fluor 532
NBP3-28355AF532
Alexa Fluor 594
NBP3-28355AF594
Alexa Fluor 647
NBP3-28355AF647
Alexa Fluor 700
NBP3-28355AF700
Alexa Fluor 750
NBP3-28355AF750
Allophycocyanin
NBP3-28355APC
Biotin
NBP3-28355B
CoraFluor 1
NBP3-28355CL1
DyLight 350
NBP3-28355UV
DyLight 405
NBP3-28355V
DyLight 488
NBP3-28355G
DyLight 550
NBP3-28355R
DyLight 594
NBP3-28355DL594
DyLight 650
NBP3-28355C
DyLight 680
NBP3-28355FR
DyLight 755
NBP3-28355IR
FITC
NBP3-28355F
HRP
NBP3-28355H
Janelia Fluor 525
NBP3-28355JF525
Janelia Fluor 549
NBP3-28355JF549
Janelia Fluor 646
NBP3-28355JF646
Janelia Fluor 669
NBP3-28355JF669
PE
NBP3-28355PE
PerCP
NBP3-28355PCP
mFluor Violet 450 SE
NBP3-28355MFV450
mFluor Violet 500 SE
NBP3-28355MFV500
mFluor Violet 610 SE
NBP3-28355MFV610
Novus Biologicals offers 100% Guarantee

FCRN/FCGRT Antibody (rozanolixizumab) - Humanized, IgG4SP Summary

Description
Expressed from CHO. The heavy chain type is huIgG4SP, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Also known as 'rozanolixizumab'.

IgG4SP is human IgG4 with S228P mutation.

Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
FcRn (FCGRT & B2M)
Isotype
IgG4
Clonality
Monoclonal
Host
Human
Gene
FCGRT
Purity
Protein A purified
Endotoxin Note
< 0.001EU/ug,determined by LAL method.
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional

Reactivity Notes

Predicted species reactivity: Cynomolgus

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A purified
Reconstitution Instructions
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Alternate Names for FCRN/FCGRT Antibody (rozanolixizumab) - Humanized, IgG4SP

  • alpha-chain
  • Fc fragment of IgG, receptor, transporter, alpha
  • FCGRT
  • FcRn alpha chain
  • FCRN
  • FCRNimmunoglobulin receptor, intestinal, heavy chain
  • IgG Fc fragment receptor transporter alpha chain
  • IgG receptor FcRn large subunit p51
  • major histocompatibility complex class I-like Fc receptor
  • Neonatal Fc receptor
  • neonatal Fc-receptor for Ig

Background

The FCGRT gene encodes a 365 amino acid long, 39 kDA IgG receptor FcRn large subunit p51 protein that transfers immunoglobulin G antibodies across the placenta from mother to fetus, as well as functions to protect the antibody from degradation. FCGRT interacts with genes CA6, ELANE, AZGP1, B2M, and ALB. It has been linked to diseases such as: lupus, nephritis, leukemia, arthritis, immunodeficiency, epidermolysis bullosa acquisita, persistent fetal circulation syndrome, and pemphigus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Albumin Antibody
(188835) [Unconjugate ...
MAB1455
Simple Western Albumin Antibody (188835) [Unconjugated] - Serum
Immunocytochemistry Albumin Antibody (188835) [Unconjugated] - Serum
Immunohistochemistry Albumin Antibody (188835) [Unconjugated] - Serum
(3 Reviews)
(54 Publications)
Species: Hu
Applications: CyTOF-ready, Dual ISH-IHC, ICC, IHC, ICFlow, Simple Western, WB
MHC Class I
Antibody (OX18) - BSA
NB120-6405
Flow Cytometry MHC Class I Antibody (OX18) - BSA Free
Immunocytochemistry/ Immunofluorescence MHC Class I Antibody (OX18) - BSA Free
Immunocytochemistry/ Immunofluorescence MHC Class I Antibody (OX18) - BSA Free
(37 Publications)
Species: Rt
Applications: B/N, CyTOF-ready, EM, ELISA, Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP
TNF-alpha
[Unconjugated]
210-TA
SDS-PAGE TNF-alpha [Unconjugated]
Bioactivity TNF-alpha [Unconjugated]
SEC-MALS TNF-alpha [Unconjugated]
(3 Reviews)
(822 Publications)
Species: Hu
Applications: BA
NOD2 Antibody
(2D9) - BSA Free
NB100-524
Flow Cytometry NOD2 Antibody (2D9) - BSA Free
Flow Cytometry NOD2 Antibody (2D9) - BSA Free
Immunohistochemistry-Frozen NOD2 Antibody (2D9) - BSA Free
(1 Review)
(26 Publications)
Species: Hu, Mu
Applications: Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
HLA DQ/DR/DP
Antibody (HLA-Pan/296 ...
NBP2-79843
Protein Array HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free
Immunocytochemistry/ Immunofluorescence HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free
Western Blot HLA DQ/DR/DP Antibody (HLA-Pan/2967R) - Azide and BSA Free
Species: Hu
Applications: CyTOF-ready, ELISA, Flow, ICC/IF, IHC, IHC-P, PA, WB
CTLA-4
[Unconjugated]
7268-CT
Bioactivity CTLA-4 [Unconjugated]
(3 Publications)
Species: Hu
Applications: BA
Fc gamma
RIIIA/CD16a [Unconjug
4325-FC
SDS-PAGE Fc gamma RIIIA/CD16a [Unconjugated]
Binding Activity Fc gamma RIIIA/CD16a [Unconjugated]
SEC-MALS Fc gamma RIIIA/CD16a [Unconjugated]
(21 Publications)
Species: Hu
Applications: Bind
Mouse IgG3 Isotype
Control (133316) [Unc ...
MAB007
Control Mouse IgG3 Isotype Control (133316) [Unconjugated]
(10 Publications)
Species: Mu
Applications: Ctrl
Erythropoietin/EPO
[HRP]
MEP00B
N/A Erythropoietin/EPO [HRP]
N/A Erythropoietin/EPO [HRP]
(105 Publications)
Species: Mu
Applications: ELISA
C1q Antibody
NBP1-87492
Western Blot C1q Antibody
Immunohistochemistry-Paraffin C1q Antibody
Immunohistochemistry-Paraffin C1q Antibody
(3 Publications)
Species: Hu
Applications: IHC, IHC-P, WB
Ovalbumin Antibody
NB600-922
Western Blot Ovalbumin Antibody
Western Blot Ovalbumin Antibody
Western Blot Ovalbumin Antibody
(10 Publications)
Species: Ch
Applications: ELISA, IHC, Single-Cell Western, WB
CD1c/BDCA-1
Antibody (OTI2F4)
NBP2-46123
Immunocytochemistry/ Immunofluorescence CD1c/BDCA-1 Antibody (OTI2F4)
Immunohistochemistry CD1c/BDCA-1 Antibody (OTI2F4)
Immunohistochemistry CD1c/BDCA-1 Antibody (OTI2F4)
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
CD1b Antibody
(737249) [Unconjugate
MAB7446
Flow Cytometry CD1b Antibody (737249) [Unconjugated]
(1 Publication)
Species: Hu
Applications: CyTOF-ready, Flow
CD1a Antibody
(NA1/34-HLK)
NB100-64852
Flow Cytometry CD1a Antibody (NA1/34-HLK)
Flow Cytometry CD1a Antibody (NA1/34-HLK)
Immunohistochemistry-Frozen CD1a Antibody (NA1/34-HLK)
(1 Review)
(9 Publications)
Species: Hu
Applications: Flow, IF, IHC, IHC-Fr
CD4 Antibody - BSA
Free
NBP1-19371
Immunohistochemistry-Frozen CD4 Antibody - BSA Free
Immunohistochemistry-Paraffin CD4 Antibody - BSA Free
Flow Cytometry CD4 Antibody - BSA Free
(9 Reviews)
(52 Publications)
Species: Ca, Hu, Mu, Po, Rb, Rt
Applications: Dual ISH-IHC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, Simple Western, WB
Fc gamma RI/CD64
[Unconjugated]
1257-FC
Binding Activity Fc gamma RI/CD64 [Unconjugated]
(24 Publications)
Species: Hu
Applications: Bind
HFE Antibody (1G12)
H00003077-M01
Western Blot HFE Antibody (1G12)
Immunocytochemistry/ Immunofluorescence HFE Antibody (1G12)
Western Blot HFE Antibody (1G12)
(2 Reviews)
(1 Publication)
Species: Hu
Applications: ELISA, ICC/IF, WB
FCRN/FCGRT
Antibody (rozanolixiz ...
NBP3-28355
FCRN/FCGRT Antibody (rozanolixizumab) - Humanized, IgG4SP
Species: Hu
Applications: ELISA, Flow, Func

Publications for FCRN/FCGRT Antibody (NBP3-28355) (0)

There are no publications for FCRN/FCGRT Antibody (NBP3-28355).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for FCRN/FCGRT Antibody (NBP3-28355) (0)

There are no reviews for FCRN/FCGRT Antibody (NBP3-28355). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for FCRN/FCGRT Antibody (NBP3-28355) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional FCRN/FCGRT Products

Research Areas for FCRN/FCGRT Antibody (NBP3-28355)

Find related products by research area.

Blogs on FCRN/FCGRT.

Check out the latest blog posts on FCRN/FCGRT.
FcRn - neonatal Fc receptor encoded by the FCGRT gene
Antibodies play an important role in the innate immune system by circulating in the bloodstream to fight off invading pathogens. IgG is the most prevalent of the five classes of antibodies (IgA, IgD, IgE, IgG, and IgM) and is the only one transmit...  Read full blog post.
Read our latest blog and use the new citation tool on bio-techne.com

Customers Who Bought This Also Bought

Contact Information

Product PDFs

  SDS
  PDF Datasheet
  Request CofA

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our FCRN/FCGRT Antibody (rozanolixizumab) - Humanized, IgG4SP and receive a gift card or discount.


Bioinformatics

Gene Symbol FCGRT
Uniprot