Immunohistochemistry-Frozen: CD1a Antibody (NA1/34-HLK) [NB100-64852] - Immunoperoxidase staining of human tonsil cryosection using Mouse anti Human CD1a antibody followed by HISTAR detection system. Medium power
Flow Cytometry: CD1a Antibody (NA1/34-HLK) [NB100-64852] - Analysis using the FITC conjugate of NB100-64852. Staining of MOLT 4 cells.
Immunohistochemistry-Frozen: CD1a Antibody (NA1/34-HLK) [NB100-64852] - mmunoperoxidase staining of human tonsil cryosection using Mouse anti Human CD1a antibody followed by HISTAR detection system. Low power
Flow Cytometry: CD1a Antibody (NA1/34-HLK) [NB100-64852] - Analysis using the Biotin conjugate of NB100-64852. Staining of MOLT 4 cells with CD1a antibody.
NB100-64852 recognizes the human CD1a cell surface glycoprotein, a 49kD molecule expressed in association with beta 2 microglobulin. CD1a is expressed strongly by cortical thymocytes, and also by Langerhans cells and interdigitating cells.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
CD1A
Purity
Protein A purified
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Species Cross Reactivity: Dog, Cynomolgus monkey Use in Canine reported in scientific literature (PMID:31837774).
Packaging, Storage & Formulations
Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein A purified
Alternate Names for CD1a Antibody (NA1/34-HLK)
CD1
CD1a antigen
CD1A antigen, a polypeptide
CD1a molecule
CD1a
cluster of differentiation 1 A
cortical thymocyte antigen CD1A
differentiation antigen CD1-alpha-3
epidermal dendritic cell marker CD1a
FCB6
hTa1 thymocyte antigen
HTA1
R4
T6
T-cell surface antigen T6/Leu-6
T-cell surface glycoprotein CD1a
Background
All CD1 molecules, except CD1e, are cell surface glycoproteins that are structurally related to the MHC molecules, however, in distinction, CD1 proteins are essentially non polymorphic. CD1 has considerable structural homology with both MHC class I and class II molecules, and CD1 molecules are involved in T cell activation. In contrast to MHC, however, CD1 molecules appear to present predominantly non peptide molecules originating from lipids and glycolipids.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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