Home » FCRN/FCGRT » FCRN/FCGRT Antibodies » FCRN/FCGRT Antibody (FCGRT/2932) [PE]

FCRN/FCGRT Antibody (FCGRT/2932) [PE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC, MA
Clone
FCGRT/2932
Clonality
Monoclonal
Host
Mouse
Conjugate
PE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-08224AF350
Alexa Fluor 405
NBP3-08224AF405
Alexa Fluor 488
NBP3-08224AF488
Alexa Fluor 532
NBP3-08224AF532
Alexa Fluor 594
NBP3-08224AF594
Alexa Fluor 647
NBP3-08224AF647
Alexa Fluor 700
NBP3-08224AF700
Alexa Fluor 750
NBP3-08224AF750
Allophycocyanin
NBP3-08224APC
Biotin
NBP3-08224B
CoraFluor 1
NBP3-08224CL1
DyLight 350
NBP3-08224UV
DyLight 405
NBP3-08224V
DyLight 488
NBP3-08224G
DyLight 550
NBP3-08224R
DyLight 594
NBP3-08224DL594
DyLight 650
NBP3-08224C
DyLight 680
NBP3-08224FR
DyLight 755
NBP3-08224IR
FITC
NBP3-08224F
HRP
NBP3-08224H
Janelia Fluor 525
NBP3-08224JF525
Janelia Fluor 549
NBP3-08224JF549
Janelia Fluor 646
NBP3-08224JF646
Janelia Fluor 669
NBP3-08224JF669
PerCP
NBP3-08224PCP
Unconjugated
NBP3-08224
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP3-08224
Azide and BSA Free
NBP3-08224
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FCRN/FCGRT Antibody (FCGRT/2932) [PE] Summary

Immunogen
Recombinant fragment of human FCRN/FCGRT protein (around aa 24-215) (Exact sequence is proprietary) (Uniprot: P55899)
Localization
Cell Surface and Cytoplasmic
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
FCGRT
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
  • Protein Array
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Alternate Names for FCRN/FCGRT Antibody (FCGRT/2932) [PE]

  • alpha-chain
  • Fc fragment of IgG, receptor, transporter, alpha
  • FCGRT
  • FcRn alpha chain
  • FCRN
  • FCRNimmunoglobulin receptor, intestinal, heavy chain
  • IgG Fc fragment receptor transporter alpha chain
  • IgG receptor FcRn large subunit p51
  • major histocompatibility complex class I-like Fc receptor
  • Neonatal Fc receptor
  • neonatal Fc-receptor for Ig

Background

The FCGRT gene encodes a 365 amino acid long, 39 kDA IgG receptor FcRn large subunit p51 protein that transfers immunoglobulin G antibodies across the placenta from mother to fetus, as well as functions to protect the antibody from degradation. FCGRT interacts with genes CA6, ELANE, AZGP1, B2M, and ALB. It has been linked to diseases such as: lupus, nephritis, leukemia, arthritis, immunodeficiency, epidermolysis bullosa acquisita, persistent fetal circulation syndrome, and pemphigus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FCRN/FCGRT
Antibody (FCGRT/2932)
NBP3-08224PE
FCRN/FCGRT Antibody (FCGRT/2932) [PE]
Species: Hu
Applications: IHC, MA

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Secondary Antibodies

 

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Blogs on FCRN/FCGRT.

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FcRn - neonatal Fc receptor encoded by the FCGRT gene
Antibodies play an important role in the innate immune system by circulating in the bloodstream to fight off invading pathogens. IgG is the most prevalent of the five classes of antibodies (IgA, IgD, IgE, IgG, and IgM) and is the only one transmit...  Read full blog post.
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Bioinformatics

Gene Symbol FCGRT