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FCRN/FCGRT Antibody (CL3638) - Azide and BSA Free

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
CL3638
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
Azide and BSA Free

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-61626AF350
Alexa Fluor 405
NBP2-61626AF405
Alexa Fluor 488
NBP2-61626AF488
Alexa Fluor 532
NBP2-61626AF532
Alexa Fluor 594
NBP2-61626AF594
Alexa Fluor 647
NBP2-61626AF647
Alexa Fluor 700
NBP2-61626AF700
Alexa Fluor 750
NBP2-61626AF750
Allophycocyanin
NBP2-61626APC
Biotin
NBP2-61626B
CoraFluor 1
NBP2-61626CL1
DyLight 350
NBP2-61626UV
DyLight 405
NBP2-61626V
DyLight 488
NBP2-61626G
DyLight 550
NBP2-61626R
DyLight 594
NBP2-61626DL594
DyLight 650
NBP2-61626C
DyLight 680
NBP2-61626FR
DyLight 755
NBP2-61626IR
FITC
NBP2-61626F
HRP
NBP2-61626H
Janelia Fluor 525
NBP2-61626JF525
Janelia Fluor 549
NBP2-61626JF549
Janelia Fluor 585
NBP2-61626JF585
Janelia Fluor 635
NBP2-61626JF635
Janelia Fluor 646
NBP2-61626JF646
Janelia Fluor 669
NBP2-61626JF669
PE
NBP2-61626PE
PerCP
NBP2-61626PCP
Unconjugated
NBP2-61626
mFluor Violet 450 SE
NBP2-61626MFV450
mFluor Violet 500 SE
NBP2-61626MFV500
mFluor Violet 610 SE
NBP2-61626MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-61626
BSA Free
NBP2-61626
BSA Free
NBP2-61626-25ul
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FCRN/FCGRT Antibody (CL3638) - Azide and BSA Free Summary

Immunogen
This antibody was generated using a recombinant protein sequence of P55899, with the exact immunogen sequence remaining proprietary.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
FCGRT
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry : 1:200 - 1:500
  • Immunohistochemistry-Paraffin : 1:200 - 1:500
Application Notes
IHC-Paraffin HIER pH6 retrieval is recommended.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Lyophilized in 5% Trehalose.
Preservative
0.02% Sodium Azide
Purity
Protein A purified

Alternate Names for FCRN/FCGRT Antibody (CL3638) - Azide and BSA Free

  • alpha-chain
  • Fc fragment of IgG, receptor, transporter, alpha
  • FCGRT
  • FcRn alpha chain
  • FCRN
  • FCRNimmunoglobulin receptor, intestinal, heavy chain
  • IgG Fc fragment receptor transporter alpha chain
  • IgG receptor FcRn large subunit p51
  • major histocompatibility complex class I-like Fc receptor
  • Neonatal Fc receptor
  • neonatal Fc-receptor for Ig

Background

The FCGRT gene encodes a 365 amino acid long, 39 kDA IgG receptor FcRn large subunit p51 protein that transfers immunoglobulin G antibodies across the placenta from mother to fetus, as well as functions to protect the antibody from degradation. FCGRT interacts with genes CA6, ELANE, AZGP1, B2M, and ALB. It has been linked to diseases such as: lupus, nephritis, leukemia, arthritis, immunodeficiency, epidermolysis bullosa acquisita, persistent fetal circulation syndrome, and pemphigus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Blogs on FCRN/FCGRT.

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FcRn - neonatal Fc receptor encoded by the FCGRT gene
Antibodies play an important role in the innate immune system by circulating in the bloodstream to fight off invading pathogens. IgG is the most prevalent of the five classes of antibodies (IgA, IgD, IgE, IgG, and IgM) and is the only one transmit...  Read full blog post.
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Bioinformatics

Gene Symbol FCGRT