FAM3B Antibody (365505)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
365505
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Formulation Size Price

FAM3B Antibody (365505) Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human FAM3B isoform B
Glu30-Ser235
Accession # NP_478066
Specificity
Detects human FAM3B in direct ELISAs and Western blots. In direct ELISAs and Western blots, 75‑100% cross-reactivity with recombinant mouse FAM3B and no cross-reactivity with recombinant human (rh) FAM3A, rhFAM3C, or rhFAM3D is observed.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
FAM3B
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for FAM3B Antibody (365505)

  • 2-21
  • C21orf11
  • C21orf76PANDER
  • chromosome 21 open reading frame 11
  • Cytokine-like protein 2-21
  • D21M16SJHU19e
  • FAM3B
  • family with sequence similarity 3, member B
  • ORF9
  • pancreatic derived factor
  • Pancreatic-derived factor
  • PANDER
  • PRED44

Background

FAM3B, also known as Pancreatic-derived factor (PANDER), is a secreted 23 kDa glycoprotein that belongs to the cytokine like-protein family. Members of this family share a four-helix bundle secondary structure similar to that found in many cytokines. As a result of alternative splicing and alternate signal peptide cleavage sites, multiple isoforms are known. FAM3B is expressed by pancreatic islet alpha and beta -cells, reproductive epithelium and a subset of neurons. Recombinant FAM3B has been shown to induce beta -cell apoptosis. The amino acid sequence of mature human FAM3B is 80% identical to that of mature mouse FAM3B.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol FAM3B
Uniprot