FAM3B Antibody (365505) Summary
Immunogen |
Mouse myeloma cell line NS0-derived recombinant human FAM3B isoform B Glu30-Ser235 Accession # NP_478066 |
Specificity |
Detects human FAM3B in direct ELISAs and Western blots. In direct ELISAs and Western blots, 75‑100% cross-reactivity with recombinant mouse FAM3B and no cross-reactivity with recombinant human (rh) FAM3A, rhFAM3C, or rhFAM3D is observed. |
Source |
N/A |
Isotype |
IgG2b |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
FAM3B |
Purity Statement |
Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
|
Buffer |
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
Preservative |
No Preservative |
Concentration |
LYOPH |
Reconstitution Instructions |
Reconstitute at 0.5 mg/mL in sterile PBS. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for FAM3B Antibody (365505)
Background
FAM3B, also known as Pancreatic-derived factor (PANDER), is a secreted 23 kDa glycoprotein that belongs to the cytokine like-protein family. Members of this family share a four-helix bundle secondary structure similar to that found in many cytokines. As a result of alternative splicing and alternate signal peptide cleavage sites, multiple isoforms are known. FAM3B is expressed by pancreatic islet alpha and beta -cells, reproductive epithelium and a subset of neurons. Recombinant FAM3B has been shown to induce beta -cell apoptosis. The amino acid sequence of mature human FAM3B is 80% identical to that of mature mouse FAM3B.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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