EVI-1 Antibody

Name: EVI-1 Antibody
Brand: Novus Biologicals
SKU: NBP1-52024
Price: 399 USD

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Western Blot: EVI-1 Antibody [NBP1-52024] - (2ug/ml) staining of A549 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Product Details

Summary

Reactivity	HuSpecies Glossary
Applications	WB, ELISA
Clonality	Polyclonal
Host	Goat
Conjugate	Unconjugated
Concentration	0.5 mg/ml

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EVI-1 Antibody Summary

Immunogen	Peptide with sequence C-DKESLHSTSH corresponding to internal region according to NP_001098547.3, NP_005232.2, NP_004982.2, NP_001157471.1, NP_001157472.1.
Epitope	C-DKESLHSTSH
Specificity	This antibody is expected to recognize all reported isoforms (NP_001098547.3; NP_005232.2; NP_004982.2; NP_001157471.1; NP_001157472.1). Reported variants represent identical protein: NP_001098548.2, NP_005232.2
Isotype	IgG
Clonality	Polyclonal
Host	Goat
Gene	MECOM
Purity	Immunogen affinity purified
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Applications/Dilutions

Dilutions	Peptide ELISA Detection limit 1:16000 Western Blot 1 - 3 ug/ml
Application Notes	WB: Approx. 170 kDa band observed in A549 and HepG2 lysates (calculated MW of 126 kDa band according to NP_001098547.3). The observed molecular weight corresponds to earlier findings with different antibodies from other sources.

Packaging, Storage & Formulations

Storage	Store at -20C. Avoid freeze-thaw cycles.
Buffer	Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative	0.02% Sodium Azide
Concentration	0.5 mg/ml
Purity	Immunogen affinity purified

Alternate Names for EVI-1 Antibody

AML1-EVI-1 fusion protein
AML1-EVI-1
ecotropic viral integration site 1
Ecotropic virus integration site 1 protein homolog
EVI1
EVI-1
EVI1MDS1-EVI1
MDS1 and EVI1 complex locus protein EVI1
MDS1 and EVI1 complex locus protein MDS1
MDS1 and EVI1 complex locus
MDS1
MECOM
MGC163392
MGC97004
Myelodysplasia syndrome 1 protein
myelodysplasia syndrome 1
Myelodysplasia syndrome-associated protein 1
oncogene EVI1
PRDM3
zinc finger protein Evi1

Background

EVI1 (ecotropic viral integration site 1) was originally identified as a gene located in the integration site of ecotropic retroviruses in the mouse genome that resulted in myeloid tumors. EVI1 is a zinc finger transcription factor that plays an important role in development and leukemogenesis. It is an oncogene that can have effects on cell proliferation, differentiation, and apoptosis. Chromosomal translocations involving EVI1 result in chronic myelogenous leukemia (CML). Alternate names for EVI1 include AML1-EVI-1 fusion protein, PRDM3, and MDS1-EV1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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EVI-1 Antibody

NBP1-52024

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Product General Protocols

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Video Protocols

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Secondary Antibodies

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DNA replication, Transcription, Translation and Splicing

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Bioinformatics

Gene Symbol	MECOM
Entrez	2122(Human) 14013(Mouse)
Uniprot	NP_001098547.3(Human)

Popular Products	Company Information	Support	Stay Connected
Antibodies Secondary Antibodies Isotype Controls Proteins and Peptides ELISA Kits Sample Size New Products	About Us Careers Novus Guarantee Contact Us Our Team	Technical Support FAQs Help Finding Antibodies Protocols

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

EVI-1 Antibody

Species Glossary

Images

Product Details

Order Details

EVI-1 Antibody Summary

Applications/Dilutions

Packaging, Storage & Formulations

Alternate Names for EVI-1 Antibody

Background

Limitations

Customers Who Viewed This Item Also Viewed...

Publications for EVI-1 Antibody (NBP1-52024) (0)

Reviews for EVI-1 Antibody (NBP1-52024) (0)

Product General Protocols

Video Protocols

FAQs for EVI-1 Antibody (NBP1-52024) (0)

Secondary Antibodies

Isotype Controls

Additional EVI-1 Products

Research Areas for EVI-1 Antibody (NBP1-52024)

Blogs on EVI-1

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Review this Product

Bioinformatics