ERAB Antibody (3O4W10)

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Western Blot: ERAB Antibody (3O4W10) [NBP3-15327] - Western blot analysis of extracts of various cell lines, using ERAB Rabbit mAb (NBP3-15327) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clone
3O4W10
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

ERAB Antibody (3O4W10) Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 162-261 of human ERAB (Q99714). QVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENPFLNGEVIRLDGAIRMQP
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
HSD17B10
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500 - 1:1000

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 50% glycerol, 0.05% BSA
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for ERAB Antibody (3O4W10)

  • 17-beta-HSD 10
  • 17-beta-hydroxysteroid dehydrogenase 10
  • 17b-HSD10
  • 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
  • ABAD
  • amyloid-beta peptide binding alcohol dehydrogenase
  • CAMR
  • DUPXp11.22
  • EC 1.1.1.178
  • EC 1.1.1.35
  • Endoplasmic reticulum-associated amyloid beta-peptide-binding protein
  • ERAB3-hydroxyacyl-CoA dehydrogenase type-2
  • HADH2AB-binding alcohol dehydrogenase
  • hydroxyacyl-Coenzyme A dehydrogenase, type II, hydroxyacyl-Coenzyme Adehydrogenase, type II
  • hydroxysteroid (17-beta) dehydrogenase 10
  • mental retardation, X-linked, syndromic 10
  • MHBD
  • Mitochondrial ribonuclease P protein 2,3-hydroxyacyl-CoA dehydrogenase type II
  • Mitochondrial RNase P protein 2
  • MRPP2HCD2
  • MRX17
  • MRX31
  • MRXS10
  • SCHAD
  • SDR5C1
  • short chain dehydrogenase/reductase family 5C, member 1
  • short chain L-3-hydroxyacyl-CoA dehydrogenase type 2
  • short chain type dehydrogenase/reductase XH98G2
  • Short-chain type dehydrogenase/reductase XH98G2
  • Type II HADH
  • XH98G2

Background

ERAB encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol HSD17B10