ERAB Products

Description

ERAB encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

Bioinformatics

Entrez	15108 Mouse 3028 Human 63864 Rat 837 Human
Uniprot	NM_001037811 Human NM_004493 Human NP_004484 Human NP_004484. Human NP_004484.1 Human Q99714 Human
Product By Gene ID	3028
Alternate Names	17-beta-HSD 10 17-beta-hydroxysteroid dehydrogenase 10 17b-HSD10 3-hydroxy-2-methylbutyryl-CoA dehydrogenase ABAD amyloid-beta peptide binding alcohol dehydrogenase CAMR DUPXp11.22 EC 1.1.1.178 EC 1.1.1.35 Endoplasmic reticulum-associated amyloid beta-peptide-binding protein ERAB3-hydroxyacyl-CoA dehydrogenase type-2 HADH2AB-binding alcohol dehydrogenase hydroxyacyl-Coenzyme A dehydrogenase, type II, hydroxyacyl-Coenzyme Adehydrogenase, type II hydroxysteroid (17-beta) dehydrogenase 10 mental retardation, X-linked, syndromic 10 MHBD Mitochondrial ribonuclease P protein 2,3-hydroxyacyl-CoA dehydrogenase type II Mitochondrial RNase P protein 2 MRPP2HCD2 MRX17 MRX31 MRXS10 SCHAD SDR5C1 short chain dehydrogenase/reductase family 5C, member 1 short chain L-3-hydroxyacyl-CoA dehydrogenase type 2 short chain type dehydrogenase/reductase XH98G2 Short-chain type dehydrogenase/reductase XH98G2 Type II HADH XH98G2

Research Areas for ERAB

Find related products by research area and learn more about each of the different research areas below.

Cancer
Lipid and Metabolism