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EDA2R/TNFRSF27/XEDAR Antibody (3C1)

Images

 
Western Blot: EDA2R/TNFRSF27/XEDAR Antibody (3C1) [H00060401-M02] - EDA2R monoclonal antibody (M02), clone 3C1. Analysis of EDA2R expression in Raw 264.7.
Sandwich ELISA: EDA2R/TNFRSF27/XEDAR Antibody (3C1) [H00060401-M02] - Detection limit for recombinant GST tagged EDA2R is approximately 1ng/ml as a capture antibody.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA
Clone
3C1
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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EDA2R/TNFRSF27/XEDAR Antibody (3C1) Summary

Immunogen
EDA2R (NP_068555, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MDCQENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHRCQSCITCAVINRVQKVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIPCTKQ
Specificity
EDA2R - ectodysplasin A2 receptor
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
EDA2R
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Sandwich ELISA
  • Western Blot 1:500
Application Notes
Antibody reactive against cell lysate and recombinant protein for western blot. It has also been used for ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for EDA2R/TNFRSF27/XEDAR Antibody (3C1)

  • ectodysplasin A2 receptor
  • EDA2R
  • EDA-A2 receptor
  • EDAA2R
  • EDA-A2R
  • EDAA2Rtumor necrosis factor receptor superfamily member XEDAR
  • EDAR2
  • TNFRSF27
  • XEDAR
  • XEDARTNFRSF27tumor necrosis factor receptor superfamily member 27
  • X-linked ectodysplasin-A2 receptor

Background

EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that are encoded by the anhidrotic ectodermal dysplasia (EDA) gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. The protein encoded by this gene specifically binds to EDA-A2 isoform. This protein is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains 3 cysteine-rich repeats and a single transmembrane domain but lacks an N-terminal signal peptide. Multiple alternatively spliced transcript variants have been found for this gene, but some variants lack sufficient support.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol EDA2R
Entrez
OMIM
Uniprot