Draxin/C1orf187 Antibody

Images

 
Western Blot: Draxin/C1orf187 Antibody [NBP3-23287] - Western blot analysis of Draxin/C1orf187 expression in rat PC12 cells (lane 1), rat P1 brain (lane 2), adult mouse brain (lane 3), and chick E9 brain (lane 4). The ...read more
Immunocytochemistry/ Immunofluorescence: Draxin/C1orf187 Antibody [NBP3-23287] - Immunocytochemical labeling of Draxin/C1orf187 in rat PC12 cells differentiated with NGF. The cells were probed with Draxin/C1orf187 ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, ChSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Draxin/C1orf187 Antibody Summary

Description
Stable for at least 1 year at -20°C.
Immunogen
Draxin/C1orf187 synthetic peptide (coupled to KLH) corresponding to amino acid residues in the C-terminal region of human Draxin/C1orf187. This peptide sequence is highly conserved in rat, mouse, and chick Draxin/C1orf187. [UniProt# Q8NBI3]
Specificity
The antibody detects a significant 50 kDa* protein corresponding to the molecular mass of Draxin/C1orf187 on SDS-PAGE immunoblots of rat PC12 cells, rat P1 brain, and chick E9 brain. The antibody also shows low expression of draxin in adult mouse brain.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DRAXIN
Purity
Antigen Affinity-purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:100
  • Western Blot 1:1000
Theoretical MW
50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C.
Buffer
PBS, 1 mg/ml BSA and 50% glycerol
Preservative
0.05% Sodium Azide
Purity
Antigen Affinity-purified

Alternate Names for Draxin/C1orf187 Antibody

  • AGPA3119
  • C1orf187
  • chromosome 1 open reading frame 187
  • dorsal inhibitory axon guidance protein
  • Dorsal repulsive axon guidance protein
  • Draxin
  • FLJ34999
  • MGC117222
  • Neucrin
  • UNQ3119

Background

Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures.Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neuriteoutgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interactionwith LRP6, thereby acting as an antagonist of Wnt signaling pathway

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DRAXIN