Dnmt2 Antibody (102B1259.2)

Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting and is essential for mammalian development. Dnmt2 is expressed at low levels in adult tissues and its inactivation does not affect DNA methylation or maintenance of methylation. Dnmt2 contains all the sequence motifs diagnostic of DNA (cytosine-5)-methyltransferases but appears to lack the large N-terminal regulatory domain common to other eukaryotic methyltransferases.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Mouse, Zebrafish.

We have publications tested in 1 application: WB.

Showing Publications 1 - 2 of 2.

Publications using NB200-587	Applications	Species
Su ZY, Zhang C, Lee JH et al. Requirement and Epigenetics Reprogramming of Nrf2 in Suppression of Tumor Promoter TPA-Induced Mouse Skin Cell Transformation by Sulforaphane. Cancer Prev Res (Phila). 2014-03-01 [PMID: 24441674] (WB, Mouse) Details: JB6 P+ mouse epidermal cells, Fig 6.	WB	Mouse
Rai K, Chidester S, Zavala CV et al. Dnmt2 functions in the cytoplasm to promote liver, brain, and retina development in zebrafish. Genes Dev. 2007-02-01 [PMID: 17289917] (WB, Zebrafish) Details: WB (zebrafish embryos), Fig. 2.	WB	Zebrafish

Images	Ratings	Applications	Species	Date	Details
	5 reviewed by: Verified Customer	ICC	Human	08/10/2021	View Summary Application Immunocytochemistry Sample Tested HeLa cells Species Human Lot 102B1259.2

Array NB200-587

• Dnmt2 Antibodies
• Dnmt2 Lysate
• Dnmt2 Proteins