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DNAM-1/CD226 Antibody (102511) [Janelia Fluor® 669]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, B/N, CyTOF-ready
Clone
102511
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 669

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB666U-100UG
Alexa Fluor 405
FAB666V-100UG
Alexa Fluor 488
FAB666G-100UG
Alexa Fluor 532
FAB666X
Alexa Fluor 594
FAB666T-100UG
Alexa Fluor 647
FAB666R-100UG
Alexa Fluor 700
FAB666N-100UG
Alexa Fluor 750
FAB666S-100UG
Allophycocyanin
FAB666A
Allophycocyanin/Cy7
FAB666APCCY7
Biotin
FAB666B
CoraFluor 1
FAB666CL1
DyLight 350
FAB666D
DyLight 405
FAB666E
DyLight 488
FAB666K
DyLight 550
FAB666L
DyLight 594
FAB666M
DyLight 650
FAB666W
DyLight 680
FAB666Y
DyLight 755
FAB666Z
Fluorescein
FAB666F
HRP
FAB666H
Janelia Fluor 525
FAB666JF525
Janelia Fluor 549
FAB666I
Janelia Fluor 585
FAB666JF585
Janelia Fluor 635
FAB666JF635
Janelia Fluor 646
FAB666J
PE/Atto594
FAB666PEATT594
PE/Cy5.5
FAB666PECY55
PE/Cy7
FAB666PECY7
PerCP
FAB666C
Phycoerythrin
FAB666P
Unconjugated
MAB666-100
mFluor Violet 450 SE
FAB666MFV450
mFluor Violet 500 SE
FAB666MFV500
mFluor Violet 610 SE
FAB666MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB666-100
Carrier Free
FAB666F
Carrier Free
FAB666P
Carrier Free
FAB666A
Carrier Free
MAB666-SP
Carrier Free
MAB666-100
Carrier Free
MAB666-500
Carrier Free
FAB666S-100UG
Carrier Free
FAB666R-100UG
Carrier Free
FAB666N-100UG
Carrier Free
FAB666G-100UG
Carrier Free
FAB666V-100UG
Carrier Free
FAB666U-100UG
Carrier Free
FAB666T-100UG
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DNAM-1/CD226 Antibody (102511) [Janelia Fluor® 669] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human DNAM-1/CD226
Glu19-Asn247 (predicted)
Accession # Q15762
Specificity
Detects human DNAM-1/CD226 in direct ELISAs and Western blots.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CD226
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Neutralization
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for DNAM-1/CD226 Antibody (102511) [Janelia Fluor® 669]

  • CD226 antigenplatelet and T cell activation antigen 1
  • CD226 molecule
  • CD226
  • DNAM1
  • DNAM-1
  • DNAM1adhesion glycoprotein
  • DNAM-1DNAX accessory molecule-1
  • DNAX accessory molecule 1
  • PTA1
  • T lineage-specific activation antigen 1 antigen
  • TLiSA1

Background

CD226 is a 65kD type I transmembrane glycoprotein, known as DNAM-1 (DNAX accessory molecule-1), PTA1(platelet and T cell activation antigen 1), or TLiSA1 (T lineage-specific activation antigen 1 antigen). It belongs to immunoglobulin superfamily containing 2 Ig-like domains, is expressed on majority of T lymphocytes, NK cells, monocytes, platelets, and a subset of B cells, activated endothelial cells. DNAM-1 is also expressed on CD8+ (but not CD8-) dendritic cells in mouse model. CD226 is an adhesion molecule involved in CTL and NK cell-mediated cytotoxicity. It has been identified that CD155 (poliovirus receptor, PVR) and CD112 (nectin-2, PRR-2) are CD226 ligands. DX11 antibody is able to inhibit CTL and NK cell-mediated cytotoxicity, and to block T cell cytokine production.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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DNAM-1/CD226
Antibody (102511) [Ja ...
FAB666JF669
DNAM-1/CD226 Antibody (102511) [Janelia Fluor® 669]
Species: Hu
Applications: WB, Flow, B/N, CyTOF-ready

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Bioinformatics

Gene Symbol CD226