Desmoglein-3 Antibody - BSA Free

Images

 
Orthogonal Strategies: Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54729] - Staining in human esophagus and stomach tissues using anti-DSG3 antibody. Corresponding DSG3 RNA-seq data are presented ...read more
Independent Antibodies: Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54729] - Staining of human colon, esophagus, lymph node and testis using Anti-DSG3 antibody NBP2-54729 (A) shows similar protein ...read more
Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54729] - Staining of human testis.
Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54729] - Staining of human stomach shows low expression as expected.
Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54729] - Staining of human esophagus shows high expression.
Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54729] - Staining of human colon.
Immunohistochemistry-Paraffin: Desmoglein-3 Antibody [NBP2-54729] - Staining of human lymph node.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free

Order Details

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Catalog# & Formulation Size Price

Desmoglein-3 Antibody - BSA Free Summary

Immunogen
This antibody was developed against a Recombinant Protein corresponding to amino acids: SSPSVVVSARTLNNRYTGPYTFALEDQPVKLPAVWSITTLNATSALLRAQEQIPPGVYHISLVLTDSQNNRCEMPRSLTLEVCQCDNRGICGTSY
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DSG3
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Desmoglein-3 Recombinant Protein Antigen (NBP2-54729PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Desmoglein-3 Antibody - BSA Free

  • Cadherin family member 6
  • CDHF6
  • CDHF6130-kD pemphigus vulgaris antigen
  • desmoglein 3 (pemphigus vulgaris antigen)
  • desmoglein 3
  • Desmoglein3
  • Desmoglein-3
  • DKFZp686P23184,130 kDa pemphigus vulgaris antigen
  • DSG3
  • pemphigus vulgaris antigen
  • PVA

Background

Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Blogs on Desmoglein-3.

Epithelial-Mesenchymal Transition (EMT) Markers
Epithelial-Mesenchymal Transition (EMT) is the trans-differentiation of stationary epithelial cells into motile mesenchymal cells. During EMT, epithelial cells lose their junctions and apical-basal polarity, reorganize their cytoskeleton, undergo a...  Read full blog post.

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Bioinformatics

Gene Symbol DSG3