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Desmin Antibody (RM234)

Images

 
Western Blot: Desmin Antibody (RM234) [NBP2-61527] - Western Blot of mouse heart tissue lysates using NBP2-61527 at a 1:1000 dilution
Immunohistochemistry-Paraffin: Desmin Antibody (RM234) [NBP2-61527] - Immunohistochemical staining of formalin fixed and paraffin embedded human heart tissue sections using NBP2-61527 at a 1:4000 dilution

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, Simple Western, IHC
Clone
RM234
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Desmin Antibody (RM234) Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
A peptide corresponding to Human Desmin
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
DES
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:1000-1:4000
  • Immunohistochemistry-Paraffin 1:1000-1:4000
  • Simple Western 1:50
  • Western Blot 1:1000-1:2000
Application Notes
See Simple Western Antibody Database for Simple Western validation: Separated by size; antibody dilution of 1:50; observed molecular weight was ~59 kDa; matrix was 12-230 kDa; detected by Chemiluminescence.
Publications
Read Publication using NBP2-61527.

Reactivity Notes

This antibody may also react to rat and Bovine Desmin, as predicted by immunogen homology.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
50% Glycerol/PBS, 1% BSA
Preservative
0.09% Sodium Azide
Purity
Protein A purified

Alternate Names for Desmin Antibody (RM234)

  • CMD1I
  • CMD1IFLJ41013
  • CSM1
  • CSM2
  • DES
  • Desmin
  • FLJ12025
  • FLJ39719
  • FLJ41793
  • intermediate filament protein

Background

Desmin is the protein subunit of muscle-type intermediate filaments (IFs). Desmin is one of the five major groups of IFs and is found predominantly in skeletal, cardiac, and smooth muscle.DE-U-10 labels desmin in tumors derived from muscle tissue (leiomyomas and rhabdomyosarcomas) (Debus E et al.).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Desmin Antibody (NBP2-61527)(1)


Showing Publication 1 - 1 of 1.
Publication using NBP2-61527 Applications Species
Hernandez M, Woerner D, Brooks J et al. Influence of Aging Temperature and Duration on Spoilage Organism Growth, Proteolytic Activity, and Related Chemical Changes in Vacuum-Packaged Beef Longissimus Meat and Muscle Biology 2022-07-13

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for Desmin Antibody (NBP2-61527) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for Desmin Antibody (NBP2-61527)

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Blogs on Desmin.

Alpha-smooth muscle actin and the modulation of endothelial and epithelial cell biology
Actin is essential for a wide range of cell functions, ranging from cell division and chromatin remodeling to vesicle trafficking and maintenance of cellular structure. In fact, mislocalization of actin to cell junctions during development leads t...  Read full blog post.

Vimentin in Wound Healing
Vimentin is a fundamental 10 nm type III intermediate filament (IF) protein found in many mesenchymal and epithelia tissues, tissue culture cells, and developing neuronal and astrocytic precursor cells of the central nervous system. It frequently co-p...  Read full blog post.

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Bioinformatics

Gene Symbol DES