DAP1 Antibody Summary
Immunogen |
The immunogen this antibody was made to, maps to a region between residue 52 and 102 of human Death-Associated Protein using the numbering given in entry NP_004385.1 (GeneID 1611). |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
DAP |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunoprecipitation 2 - 10 ug/mg
- Western Blot 1:500 - 1:2500
|
Packaging, Storage & Formulations
Storage |
Store at 4C. Do not freeze. |
Buffer |
Tris-Citrate/Phosphate (pH 7.0 - 8.0) |
Preservative |
0.09% Sodium Azide |
Concentration |
1.0 mg/ml |
Purity |
Immunogen affinity purified |
Alternate Names for DAP1 Antibody
Background
Death associated protein 1 (DAP-1) is a 15-kDa protein that functions as a positive mediator of cell death initiated by interferon (IFN-) gamma (1,2). DAP-1 is proline rich and possesses one SH3 binding motif, as well as several consensus protein kinase phosphorylation sites (1). It is localized to the cytoplasm, but the detailed mechanism of its pro-apoptotic function is unclear. DAP-1 and DAP kinase, a unique, 160-kDa calmodulin-dependent serine/threonine kinase, are both unique candidates for positive mediators of programmed cell death induced by IFN-gamma (3).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Product General Protocols
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