DAP1 Products

Description

Death associated protein 1 (DAP-1) is a 15-kDa protein that functions as a positive mediator of cell death initiated by interferon (IFN-) gamma (1,2). DAP-1 is proline rich and possesses one SH3 binding motif, as well as several consensus protein kinase phosphorylation sites (1). It is localized to the cytoplasm, but the detailed mechanism of its pro-apoptotic function is unclear. DAP-1 and DAP kinase, a unique, 160-kDa calmodulin-dependent serine/threonine kinase, are both unique candidates for positive mediators of programmed cell death induced by IFN-gamma (3).

Bioinformatics

Entrez	1611 Human
Uniprot	AAH02726 Human NP_004385 Human P51397 Human
Product By Gene ID	1611
Alternate Names	DAP1 DAP-1 death-associated protein 1 death-associated protein MGC99796

Research Areas for DAP1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cellular Markers