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Cytokeratin 19 Antibody (A53-B/A2.26) [HRP]

 
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Product Details

Summary
Reactivity Hu, Ma(-), Rt(-)Species Glossary
Applications WB, Simple Western, Flow, ICC/IF, IHC, CyTOF-ready
Clone
A53-B/A2.26
Clonality
Monoclonal
Host
Mouse
Conjugate
HRP

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-33134AF350
Alexa Fluor 405
NBP2-33134AF405
Alexa Fluor 488
NBP2-33134AF488
Alexa Fluor 532
NBP2-33134AF532
Alexa Fluor 594
NBP2-33134AF594
Alexa Fluor 647
NBP2-33134AF647
Alexa Fluor 700
NBP2-33134AF700
Alexa Fluor 750
NBP2-33134AF750
Allophycocyanin
NBP2-33134APC
Biotin
NBP2-33134B
DyLight 350
NBP2-33134UV
DyLight 405
NBP2-33134V
DyLight 488
NBP2-33134G
DyLight 550
NBP2-33134R
DyLight 594
NBP2-33134DL594
DyLight 650
NBP2-33134C
DyLight 680
NBP2-33134FR
DyLight 755
NBP2-33134IR
FITC
NBP2-33134F
Janelia Fluor 549
NBP2-33134JF549
Janelia Fluor 646
NBP2-33134JF646
PE
NBP2-33134PE
PerCP
NBP2-33134PCP
Unconjugated
NBP2-15186-0.1mg
mFluor Violet 450 SE
NBP2-33134MFV450
mFluor Violet 500 SE
NBP2-33134MFV500
mFluor Violet 610 SE
NBP2-33134MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-15186-0.1mg
Azide and BSA Free
NBP2-33134
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Cytokeratin 19 Antibody (A53-B/A2.26) [HRP] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Immunogen
Human breast cancer MCF-7 cells
Epitope
aa 312-335
Localization
Cytoplasmic
Marker
Pancreatic Stem Cell Marker
Specificity
This monoclonal antibody reacts with the rod domain of human cytokeratin-19 (CK19), a polypeptide of 40kDa. Its epitope maps between amino acid 312-335. CK19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50%-60% of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.
Isotype
IgG2a Lambda
Clonality
Monoclonal
Host
Mouse
Gene
KRT19
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Simple Western
  • Western Blot
Readout System

Reactivity Notes

Does not react with Rat or Ferret.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Protein A or G purified

Alternate Names for Cytokeratin 19 Antibody (A53-B/A2.26) [HRP]

  • 40-kDa keratin intermediate filament
  • CK19
  • CK-19
  • Cytokeratin 19
  • EndoC
  • K19
  • K1CS
  • keratin 19
  • keratin, type I cytoskeletal 19
  • keratin, type I, 40-kd
  • keratin-19
  • Krt19
  • MGC15366

Background

Cytokeratin 19 (also known as Keratin, type I cytoskeletal 19) belongs to the keratin family which consists of fibrous proteins that make up the framework of epithelial cells. Cytokeratin 19 plays a role in the organization of myofibers. This protein is known to have interactions with ZNF638, FANCG, FAM107A, KRT15 and EXOC8. Cytokeratin 19 has been studied in relation to several disorders and diseases including chordoma, adenoma, hamartoma, adenoiditis, carcinoma, and liver disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol KRT19