Cytochrome P450 1A2 Antibody (D15) - BSA Free Summary
Immunogen |
MC1a (Preparation C31B4, rat liver cytochrome P4501A2) |
Localization |
Liver endoplasmic reticulum, membrane bound. |
Specificity |
D15 cross reacts with CYP1A1 & CYP1A2. |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
CYP1A2 |
Purity |
Protein A purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- ELISA 1:100 - 1:2000
- Immunocytochemistry/ Immunofluorescence 1:10 - 1:500
- Immunohistochemistry 1:10 - 1:500
- Western Blot 1:100 - 1:2000
|
Application Notes |
Positive control(s): MCF7 cells (ICC/IF) or human normal liver (IHC). |
Theoretical MW |
52 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
PBS |
Preservative |
0.02% Sodium Azide |
Concentration |
1 mg/ml |
Purity |
Protein A purified |
Alternate Names for Cytochrome P450 1A2 Antibody (D15) - BSA Free
Background
In animals, P450 enzymes serve two major functions: (1) biosynthesis of steroids, fatty acids, and bile acids; (2) metabolism of endogenous and a wide variety of exogenous substrates, such as toxins and drugs. The four major families involved in drug metabolism are CYP 1,2,3, and 4. CYP1A2 is an aryl hydrocarbon hydroxylase involved in the metabolism of endogenous compounds and xenobiotics. It is one of the major drug metabolising enzymes in humans.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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