CRHR1/CRF1 Antibody - BSA Free Summary
Description |
Product can be stored undiluted at 4C for up to 1 month. |
Immunogen |
Synthetic 18 amino acid peptide from N-terminal extracellular domain of human CRHR1/CRF1. |
Epitope |
N-Terminus extracellular domain |
Specificity |
Human CRF1. BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Predicted Species |
Mouse (94%), Hamster (94%). Backed by our 100% Guarantee. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
CRHR1 |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry
- Immunohistochemistry-Paraffin 21 ug/ml
|
Application Notes |
. |
Reactivity Notes
Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Canine (89%), Bat (89%), Bovine (89%), Porcine (89%), Zebrafish (89%), Opossum (83%), Turkey (83%).
Packaging, Storage & Formulations
Storage |
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. |
Buffer |
PBS |
Preservative |
0.1% Sodium Azide |
Concentration |
1.0 mg/ml |
Purity |
Immunogen affinity purified |
Alternate Names for CRHR1/CRF1 Antibody - BSA Free
Background
Corticotropin-releasing factor receptor 1 (CRFR1/CRHR1), a Corticotropin-Releasing Factor Receptor, is involved in mediating the stress response and anxiety-related behaviors. Mutations of the receptor reduce anxiety-related behaviors and may be involved in the pathogenesis of Cushing disease. Multiple isoforms of CRFR1 are produced by alternative splicing. CRFR1 has been reported to be expressed in the pituitary, adrenal gland, brain, colon, ovary, placenta, testis, white blood cells, and skin. ESTs have been isolated from human brain, eye, colon, and embryo libraries.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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