CRB1 Antibody - BSA Free

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Western Blot: CRB1 Antibody [NBP2-41201] - Analysis of CRB1 in human small intestine Tissue lysate with CRB1 antibody at 1 ug/mL.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

CRB1 Antibody - BSA Free Summary

Immunogen
Antibody was raised against an 18 amino acid peptide near the center of human CRB1. The immunogen is located within amino acids 780 - 830 of CRB1. Amino Acid Squence: ISLKIKPYKIELYQSSQ
Specificity
Alternatively spliced transcript variants have been observed. CRB1 antibody i spredicted to not cross-react with CRB2.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CRB1
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot 1 - 2 ug/mL
Theoretical MW
142 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (82%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for CRB1 Antibody - BSA Free

  • crumbs homolog 1 (Drosophila)
  • LCA8

Background

CRB1, also known as Protein crumbs homolog 1, contains several isoforms that are 154 kDa, 151 kDa, 142 kDa, 104 kDa, and 95 kDa, and is involved in the development of photoreceptors in the retina. Defects and mutations in the CRB1 protein result in a variety of disorders, and more research is currently being conducted on the protein's relation to other diseases, including pigmented paravenous chorioretinal atrophy, cone-rod dystrophy, Stargardt disease, keratoconus, retinal degeneration, hyperopia, tuberous sclerosis, and blindness. The protein is linked to epithelial tight junction pathways, and interacts with INADL, MPP5, PSMD13, PRKAR1A, and DDX56.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

Additional CRB1 Products

Array NBP2-41201

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Bioinformatics

Gene Symbol CRB1