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CRB1 Antibody [CoraFluor™ 1]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
CoraFluor 1

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-41201AF350
Alexa Fluor 405
NBP2-41201AF405
Alexa Fluor 488
NBP2-41201AF488
Alexa Fluor 532
NBP2-41201AF532
Alexa Fluor 594
NBP2-41201AF594
Alexa Fluor 647
NBP2-41201AF647
Alexa Fluor 700
NBP2-41201AF700
Alexa Fluor 750
NBP2-41201AF750
Biotin
NBP2-41201B
DyLight 350
NBP2-41201UV
DyLight 405
NBP2-41201V
DyLight 488
NBP2-41201G
DyLight 550
NBP2-41201R
DyLight 594
NBP2-41201DL594
DyLight 650
NBP2-41201C
DyLight 680
NBP2-41201FR
DyLight 755
NBP2-41201IR
FITC
NBP2-41201F
HRP
NBP2-41201H
Janelia Fluor 525
NBP2-41201JF525
Janelia Fluor 549
NBP2-41201JF549
Janelia Fluor 585
NBP2-41201JF585
Janelia Fluor 635
NBP2-41201JF635
Janelia Fluor 646
NBP2-41201JF646
Janelia Fluor 669
NBP2-41201JF669
PerCP
NBP2-41201PCP
Unconjugated
NBP2-41201
mFluor Violet 450 SE
NBP2-41201MFV450
mFluor Violet 500 SE
NBP2-41201MFV500
mFluor Violet 610 SE
NBP2-41201MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-41201
BSA Free
NBP2-41201
BSA Free
NBP2-41201-0.025mg
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CRB1 Antibody [CoraFluor™ 1] Summary

Description
CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
Immunogen
Antibody was raised against an 18 amino acid peptide near the center of human CRB1. The immunogen is located within amino acids 780 - 830 of CRB1. Amino Acid Squence: ISLKIKPYKIELYQSSQ
Specificity
Alternatively spliced transcript variants have been observed. CRB1 antibody i spredicted to not cross-react with CRB2.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CRB1
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (82%)

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
No Preservative
Purity
Peptide affinity purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for CRB1 Antibody [CoraFluor™ 1]

  • crumbs homolog 1 (Drosophila)
  • LCA8

Background

CRB1, also known as Protein crumbs homolog 1, contains several isoforms that are 154 kDa, 151 kDa, 142 kDa, 104 kDa, and 95 kDa, and is involved in the development of photoreceptors in the retina. Defects and mutations in the CRB1 protein result in a variety of disorders, and more research is currently being conducted on the protein's relation to other diseases, including pigmented paravenous chorioretinal atrophy, cone-rod dystrophy, Stargardt disease, keratoconus, retinal degeneration, hyperopia, tuberous sclerosis, and blindness. The protein is linked to epithelial tight junction pathways, and interacts with INADL, MPP5, PSMD13, PRKAR1A, and DDX56.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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CRB1 Antibody
[CoraFluor™ 1]
NBP2-41201CL1
CRB1 Antibody [CoraFluor™ 1]
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Applications: WB, ELISA

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Bioinformatics

Gene Symbol CRB1