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COX-1 Antibody (596002)

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Western blot shows lysates of HepG2 human hepatocellular carcinoma cell line and B16-F10 mouse melanoma cell line. PVDF Membrane was probed with 2 µg/mL of Human COX-1 Monoclonal Antibody (Catalog # MAB37401) followed ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB
Clone
596002
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

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Catalog# & Formulation Size Price
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COX-1 Antibody (596002) Summary

Immunogen
E.coli-derived recombinant human COX-1
Asn381-Leu599
Accession # P23219
Specificity
Detects human COX-1 in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross-reactivity with recombinant human (rh) COX-4I1 and no cross-reactivity with rhCOX-1 or rhCOX-4I2 is observed.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
PTGS1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 2 ug/mL
Publications
Read Publication using MAB37401.

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Sterile PBS to a final concentration of 0.5 mg/mL.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for COX-1 Antibody (596002)

  • COX1
  • COX-1
  • COX1PGG/HS
  • COX3
  • cyclooxygenase-1
  • EC 1.14.99.1
  • PCOX1
  • PGH synthase 1
  • PGHS1
  • PGHS-1PHS1
  • PHS 1
  • prostaglandin G/H synthase 1
  • prostaglandin G/H synthase and cyclooxygenase
  • Prostaglandin H2 synthase 1
  • prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase andcyclooxygenase)
  • Prostaglandin-endoperoxide synthase 1
  • PTGHS
  • PTGS1

Background

COX-1 is an approximately 70 kDa protein that is associated with microsomal membranes. COX-1 participates in the synthesis of prostaglandins and is the enzymatic target of non-steroidal anti-inflammatory drugs. A splice variant of COX-1 is generated by internal deletion of 37 residues. Human COX-1 shares 88%‑90% amino acid sequence identity with mouse and rat COX‑1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for COX-1 Antibody (MAB37401)(1)

Reviews for COX-1 Antibody (MAB37401) (0)

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Product General Protocols

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FAQs for COX-1 Antibody (MAB37401). (Showing 1 - 1 of 1 FAQ).

  1. Please could you tell me if Novus Biologicals has an active COX1 Recombinant Protein?
    • Unfortunately we do not currently have any COX1 recombinant proteins that are expected to be active.
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Bioinformatics

Gene Symbol PTGS1
Uniprot