Complement Factor D/Adipsin Antibody (lampalizumab) - Humanized

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Immobilized human Complement Factor D,   Fc at 2 ug/mL can bind Complement Factor D/Adipsin Antibody (lampalizumab) - Humanized, EC50=0.02371 ug/mL.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, Func
Clone
lampalizumab
Clonality
Monoclonal
Host
Human
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

Complement Factor D/Adipsin Antibody (lampalizumab) - Humanized Summary

Description
Expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Also known as 'lampalizumab'.

Upon receipt, store immediately at -20C or lower for 24 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
Complement Factor D
Isotype
IgG1
Clonality
Monoclonal
Host
Human
Gene
CFD
Purity
Protein A purified
Endotoxin Note
< 0.001EU/ug,determined by LAL method.
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A purified
Reconstitution Instructions
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Alternate Names for Complement Factor D/Adipsin Antibody (lampalizumab) - Humanized

  • Adipsin
  • ADN
  • ADNcomplement factor D
  • AMBP-1
  • C3 convertase activator
  • CFD
  • complement factor D (adipsin)
  • complement factor D preproprotein
  • Complement Factor D
  • D component of complement (adipsin)
  • DF
  • EC 3.4.21
  • EC 3.4.21.46
  • PFD
  • Properdin factor DADIPSIN

Background

Adipsin is encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CFD
Uniprot