Complement C3d Antibody (C3D/2891) [DyLight 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, IHC, MA
Clone
C3D/2891
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 405

Order Details

Complement C3d Antibody (C3D/2891) [DyLight 405] Summary

Immunogen
Recombinant fragment (around aa 1250-1450) of human Complement C3d protein (exact sequence is proprietary) (Uniprot: P01024)
Localization
Plasma.
Marker
Acute Humoral Rejection Marker
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
C3
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry-Paraffin
  • Protein Array
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Complement C3d Antibody (C3D/2891) [DyLight 405]

  • AHUS5
  • ARMD9
  • ASP
  • C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
  • complement C3
  • complement component 3
  • complement component C3
  • CPAMD1acylation-stimulating protein cleavage product

Background

C3d is a fragment of the major complement protein C3, C3d is formed as a result of the deactivation of C3b.Factor I in the presence of cofactors cleaves C3b to form iC3b and C3f, Factor I and/or other proteasesthen cleaves iC3b to form C3c and C3dg. C3dg is then further cleaved by tryptic enzymes to C3g andC3d. The C3 fragments are then eliminated from circulation by phagocytic cells in the liver. C3d has amolecular weight of 34kDa. Normally C3d is present in trace amounts in plasma, however, in diseasestates where rapid complement consumption is occurring levels of C3d can be elevated.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Array NBP3-08764V

Research Areas for Complement C3d Antibody (NBP3-08764V)

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Bioinformatics

Gene Symbol C3