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Collagen XVII Antibody - Azide and BSA Free

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Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
Azide and BSA Free

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Collagen XVII Antibody - Azide and BSA Free Summary

Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1300-1400 of human Collagen XVII (NP_000485.3). SVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQGP
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
COL17A1
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:2000

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS with 50% glycerol, pH7.3.
Preservative
0.01% Thimerosal
Purity
Affinity purified

Alternate Names for Collagen XVII Antibody - Azide and BSA Free

  • 180 kDa bullous pemphigoid antigen 2
  • BA16H23.2
  • BP180
  • BP180alpha 1 type XVII collagen
  • BPA-2
  • BPAG2
  • BPAG2bA16H23.2 (collagen, type XVII, alpha 1 (BP180))
  • bullous pemphigoid antigen 2 (180kD)
  • Bullous pemphigoid antigen 2
  • COL17A1
  • Collagen 17
  • collagen alpha-1(XVII) chain
  • Collagen XVII
  • collagen XVII, alpha-1 polypeptide
  • collagen, type XVII, alpha 1
  • Collagen-17
  • ERED
  • FLJ60881
  • KIAA0204
  • LAD-1

Background

Collagen XVII encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including Methotrexate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol COL17A1