Coilin Antibody

The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: ICC/IF.

Showing Publications 1 - 2 of 2.

Publications using NBP2-15939	Applications	Species
Kannan A, Cuartas J, Gangwani P et al. Mutation in senataxin alters the mechanism of R-loop resolution in amyotrophic lateral sclerosis 4 Brain : a journal of neurology 2022-01-19 [PMID: 35045161] (ICC/IF, Human)	ICC/IF	Human
Kannan A, Bhatia K, et al. Combined deficiency of Senataxin and DNA-PKcs causes DNA damage accumulation and neurodegeneration in spinal muscular atrophy. Nucleic Acids Res 2018-09-19 [PMID: 30010942] (ICC/IF, Human)	ICC/IF	Human

Array NBP2-15939

• Coilin Antibodies
• Coilin Lysate
• Coilin Proteins