CD81 Antibody

CD81/TAPA-1 is an integral membrane protein expressed on a variety of cell types, and has a high degree of sequence homology between human and mouse. (1) CD81 is expressed on thymic stromal cells where it plays an important role in the transition of gamma delta + T cells to more mature T cells with alpha beta T cell receptors. (2) Immunohistochemical staining has revealed that its expression is localized to the subcapsular region of the thymus and, specifically, on cells that have distinct clustering patterns. It has been speculated that the ligand for CD81 is the pre-T cell receptor, which is composed of a TCR beta chain and glycoprotein pT alpha. (2) The monoclonal antibody 2F7 can block thymocyte interaction with CD81 in vitro. (2)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: ICC/IF.

Showing Publications 1 - 2 of 2.

Publications using NBP1-80701	Applications	Species
Yang H, Wu Y, Cheng M et al. Roxadustat (FG-4592) protects against ischemia-induced acute kidney injury via improving CD73 and decreasing AIM2 inflammasome activation Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2022-11-22 [PMID: 36413468]
Suzuki K, Tange M, Yamagishi R et al. SMG6 regulates DNA damage and cell survival in Hippo pathway kinase LATS2-inactivated malignant mesothelioma Cell death discovery 2022-11-05 [PMID: 36335095] (ICC/IF, Human)	ICC/IF	Human

Array NBP1-80701

• CD81 Antibodies
• CD81 ELISA Kit
• CD81 Lysate
• CD81 Proteins
• CD81 Proteins and Enzyme