Reactivity | HuSpecies Glossary |
Applications | WB, Flow, IHC, IP, CyTOF-ready |
Clone | MEM-53 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Unconjugated |
Format | BSA Free |
Concentration | 1.0 mg/ml |
Additional Information | Clone MEM-53 was used by HLDA to establish CD designation. |
Immunogen | Leukocytes of patient suffering from a LGL-type leukemia. |
Specificity | The antibody MEM-53 reacts with CD53, a 32-40 kDa tetraspanin family glycoprotein exclusivelly expressed on leukocytes; it is not present on platelets, red blood cells and non-hematopoietic cells. The antibody MEM-53 reacts also with deglycosylated molecule (molecular weight of the antigen is reduced by 15 kDa using endoglycosidase F). HLDA IV; WS Code NL 59 HLDA V; WS Code B CD53.5 HLDA V; WS Code BP BP287 HLDA V; WS Code T T-096 HLDA V; WS Code X XB004 |
Isotype | IgG1 |
Clonality | Monoclonal |
Host | Mouse |
Gene | CD53 |
Purity | Protein A purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
|
|
Application Notes | This antibody is suitable for discrimination of lymphomas from other tumors. Functional Application: The antibody MEM-53 induces activation of monocytes and B lymphocytes. This antibody is CyTOF ready. |
|
Theoretical MW | 40 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
|
Publications |
|
Storage | Store at 4C. Do not freeze. |
Buffer | PBS (pH 7.4) |
Preservative | 0.9% Sodium Azide |
Concentration | 1.0 mg/ml |
Purity | Protein A purified |
Publications using NB500-393 | Applications | Species |
---|---|---|
Morales-Martínez, M;Andón-García, D;Patiño-Santiago, KA;Parga-Ortega, JM;Hernández-Hernández, A;Aquino-Jarquin, G;Patino-Lopez, G; Identification of potential new T cell activation molecules: a Bioinformatic Approach Scientific reports 2024-09-27 [PMID: 39333573] | ||
Dunlock VME, Arp AB, Jansen E, Charrin S Dynamic regulation of CD45 by tetraspanin CD53 bioRxiv (FLOW, Human) | FLOW | Human |
Secondary Antibodies |
Isotype Controls |
Research Areas for CD53 Antibody (NB500-393)Find related products by research area.
|
CD81/TAPA1: I'm on Tapa the Cell Target of the antiproliferative 1 (TAPA1), also known as CD81, is found in the plasma membrane in lymphocytes and plays an important role in the regulation of lymphoma cell growth. This transmembrane 4 superfamily (TM4SF) protein is primarily found on... Read full blog post. |
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.