CD81 Antibody (1D6) - BSA Free

TAPA1, also known as CD81, is found in the plasma membrane in lymphocytes and is believed to play an important role in the regulation of lymphoma cell growth. This protein is primarily found on B and T cells (lymphocytes) in humans. TAPA1 appears to be involved in a variety of cellular processes including activation, proliferation and differentiation. It is believed to act as a viral receptor for HCV and may play a crucial role in cell signaling from its place embedded in the plasma membrane. Mutations affecting CD81 can cause immunodeficiency- a disease that is characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections due to a lack of an immune response.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Primate.

We have publications tested in 7 applications: Cytometric Bead Assay Standard, ELISA, IA, ICC/IF, IP, Simple Western, WB.

Showing Publications 1 - 10 of 25. Show All 25 Publications. Collapse Publications.

Publications using NB100-65805	Applications	Species
Craddock V, Mahajan A, Spikes L et al. Persistent circulation of soluble and extracellular vesicle-linked Spike protein in individuals with postacute sequelae of COVID-19 Journal of medical virology 2023-02-01 [PMID: 36756925]
Wright AB The isolation, culture-expansion, cryopreservation, characterization, and properties of umbilical cord-derived mesenchymal stromal cells and their extracellular vesicles Thesis 2021-01-01
Kolka CM, Webster J, Lepletier A et al. C5b-9 Membrane Attack Complex Formation and Extracellular Vesicle Shedding in Barrett's Esophagus and Esophageal Adenocarcinoma Frontiers in immunology 2022-03-08 [PMID: 35345676] (IA, Human)	IA	Human
Ono, K;Niwa, M;Suzuki, H;Kobayashi, NB;Yoshida, T;Sawada, M; Signal Sequence-Dependent Orientation of Signal Peptide Fragments to Exosomes International journal of molecular sciences [PMID: 35328557] (WB)	WB
Zhang Z, Hu J, Ishihara M et al. The miRNA-21-5p Payload in Exosomes from M2 Macrophages Drives Tumor Cell Aggression via PTEN/Akt Signaling in Renal Cell Carcinoma International journal of molecular sciences 2022-03-10 [PMID: 35328425] (WB, Human)	WB	Human
Rudy MJ, Coughlan C, Hixon AM et al. Density Analysis of Enterovirus D68 Shows Viral Particles Can Associate with Exosomes Microbiology spectrum 2022-02-23 [PMID: 35170992] (IP, Human)	IP	Human
Nagao K, Maeda K, Hosomi K et al. Sialyl-Tn antigen facilitates extracellular vesicle-mediated transfer of FAK and enhances motility of recipient cells Journal of biochemistry 2022-02-01 [PMID: 35106570]
Li W, Xu J, Cheng L et al. RelB promotes the migration and invasion of prostate cancer DU145 cells via exosomal ICAM1 in vitro Cellular signalling 2021-12-18 [PMID: 34933092] (WB, Human)	WB	Human
Bellio MA, Young KC, Milberg J et al. Amniotic fluid-derived extracellular vesicles: characterization and therapeutic efficacy in an experimental model of bronchopulmonary dysplasia Cytotherapy 2021-09-17 [PMID: 34538718] (ICC/IF, Human)	ICC/IF	Human
Krishnamachary B, Mahajan A, Kumar A et al. Extracellular vesicle TGF-beta 1 is linked to cardiopulmonary dysfunction in HIV American journal of respiratory cell and molecular biology 2021-05-20 [PMID: 34014809]
Tian ZF, Shen H, Fu XH et al. Interaction of hepatitis C virus envelope glycoprotein E2 with the large extracellular loop of tupaia CD81. World J Gastroenterol. 2009-01-14 [PMID: 19132776] (WB, Human)	WB	Human
Flint M, Maidens C, Loomis-Price LD et al. Characterization of hepatitis C virus E2 glycoprotein interaction with a putative cellular receptor, CD81. J Virol. 1999-08-01 [PMID: 10400713] (ELISA, WB, Human)	ELISA, WB	Human
Liu M, Ji Y, Zhu F, et al. NOMA: a high-throughput microchip for robust sequential measurements of secretions from the same single-cells bioRxiv 2021-01-24
Quan Zhou, Xueming Niu, Zhen Zhang, Kenneth O'Byrne, Arutha Kulasinghe, David Fielding, Andreas Möller, Alain Wuethrich, Richard J Lobb, Matt Trau Glycan Profiling in Small Extracellular Vesicles with a SERS Microfluidic Biosensor Identifies Early Malignant Development in Lung Cancer. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024-06-17 [PMID: 38885350]
Seungeun Yeo, Jaemyung Jang, Hyun Jin Jung, Hyeyoung Lee, Youngshik Choe Primary cilia-mediated regulation of microglial secretion in Alzheimer’s disease Frontiers in Molecular Biosciences 2023-10-23 [PMID: 37942288]
Mut M, Adiguzel Z, Cakir-Aktas C et al. Extracellular-Vesicle-Based Cancer Panels Diagnose Glioblastomas with High Sensitivity and Specificity Cancers 2023-07-26 [PMID: 37568598] (WB, Human)	WB	Human
Kim S, Lee K, Choi YS et al. Mitochondrial double-stranded RNAs govern the stress response in chondrocytes to promote osteoarthritis development Cell reports 2022-08-09 [PMID: 35947956] (WB) Details: Supplementary Figure S5.	WB
Nik Mohamed Kamal NNS, Awang RAR, Mohamad S, Shahidan WNS. Plasma- and Saliva Exosome Profile Reveals a Distinct MicroRNA Signature in Chronic Periodontitis Frontiers in Physiology 2020-11-30 [PMID: 33329037] (Simple Western)	Simple Western
Chen BH, Chang YJ, Lin S, Yang WY Hsc70/Stub1 promotes the removal of individual oxidatively stressed peroxisomes Nat Commun 2020-10-19 [PMID: 33077711] (WB, Human, Primate)	WB	Human, Primate
Roma-Rodrigues C, Fernandes AR, Baptista PV Counteracting the effect of leukemia exosomes by antiangiogenic gold nanoparticles Int J Nanomedicine 2019-08-26 [PMID: 31692567] (WB, Human)	WB	Human
Multiplexed Profiling of Single-cell Extracellular Vesicles Secretion. Ji Y, Qi D, Li L et al. Proc Natl Acad Sci U S A [PMID: 30858327] (Cytometric Bead Assay Standard, Human)	Cytometric Bead Assay Standard	Human
Ren W, Hou J, Yang C et al. Extracellular vesicles secreted by hypoxia pre-challenged mesenchymal stem cells promote non-small cell lung cancer cell growth and mobility as well as macrophage M2 polarization via miR-21-5p delivery J. Exp. Clin. Cancer Res. 2019-02-08 [PMID: 30736829] (WB, Human)	WB	Human
Otake K, Kamiguchi H, Hirozane Y. Identification of biomarkers for amyotrophic lateral sclerosis by comprehensive analysis of exosomal mRNAs in human cerebrospinal fluid BMC Med Genomics 2019-01-10 [PMID: 30630471] (WB, Human)	WB	Human
Shin H, Jeong H, Park J et al. Correlation between Cancerous Exosomes and Protein Markers Based on Surface-Enhanced Raman Spectroscopy (SERS) and Principal Component Analysis (PCA). ACS Sens. 2018-11-09 [PMID: 30381940] (WB, Human)	WB	Human
Kibria G, Ramos EK, Lee KE et al. A rapid, automated surface protein profiling of single circulating exosomes in human blood. Sci Rep. 2016-11-07 [PMID: 27819324] (WB, Human)	WB	Human
Show All 25 Publications. Collapse Publications.

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Verified Customer	DB	Canine	10/09/2020	View Summary Application Dot Blot Sample Tested cell lysate canine umbilical cord-derived mesenchymal stromal cells,Cell lysate from canine umbilical cord-derived mesenchymal stromal cells,EVs derived from canine umbilical cord-derived mesenchymal stromal cells,EVs from canine umbilical cord-derived mesenchymal stromal cells Species Canine Lot A-8

Array NB100-65805

• CD81 Antibodies
• CD81 ELISA Kit
• CD81 Lysate
• CD81 Proteins
• CD81 Proteins and Enzyme