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CD81 Antibody (M38) [DyLight 488]

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Product Details

Summary
Reactivity Hu, Mu, Fe, RbSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IP, CyTOF-ready, KO, Single-Cell Western
Clone
M38
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

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CD81 Antibody (M38) [DyLight 488] Summary

Immunogen
MOLT-4, human T-ALL cell line (NM_004356.3).
Specificity
The antibody M38 reacts with CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
CD81
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Knockout Validated
  • Single Cell Western
  • Western Blot

Reactivity Notes

Cat (100%). Use in Mouse reported in scientific publication( PMID: 32573489).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CD81 Antibody (M38) [DyLight 488]

  • CD81 antigen (target of antiproliferative 1)
  • CD81 antigen
  • CD81 molecule
  • CD81
  • CVID6
  • TAPA1
  • TAPA-1
  • Target of the antiproliferative 1
  • Tetraspanin-28
  • TSPAN28
  • Tspan-28
  • tspan-28,26 kDa cell surface protein TAPA-1
  • TSPAN28S5.7

Background

CD81/TAPA-1 is an integral membrane protein expressed on a variety of cell types, and has a high degree of sequence homology between human and mouse. (1) CD81 is expressed on thymic stromal cells where it plays an important role in the transition of gamma delta + T cells to more mature T cells with alpha beta T cell receptors. (2) Immunohistochemical staining has revealed that its expression is localized to the subcapsular region of the thymus and, specifically, on cells that have distinct clustering patterns. It has been speculated that the ligand for CD81 is the pre-T cell receptor, which is composed of a TCR beta chain and glycoprotein pT alpha. (2) The monoclonal antibody 2F7 can block thymocyte interaction with CD81 in vitro. (2)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CD81 Antibody (NBP1-44861G) (0)

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Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for CD81 Antibody (NBP1-44861G) (0)

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Secondary Antibodies

 

Isotype Controls

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CD81/TAPA1: I'm on Tapa the Cell
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Bioinformatics

Gene Symbol CD81