CD63 Antibody (460305) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

CD63, also known as LAMP-3 or ME491 (melanoma-associated antigen), is a 30-60 kDa member of the tetraspanin superfamily of protein trafficking proteins. CD63 is ubiquitously expressed and found in late endocytic vesicles, but following cell activation is also present on the plasma membrane. Interaction of CD63 with other membrane proteins or adaptors regulates cell activities such as adhesion, migration and degranulation. Extracellular regions of human CD63 share 67% and 65% amino acid sequence identity with mouse and rat CD63, respectively.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Western Blot.

Showing Publications 1 - 5 of 5.

Publications using MAB5048	Applications	Species
Dmitry Ter-Ovanesyan, Tal Gilboa, Bogdan Budnik, Adele Nikitina, Sara Whiteman, Roey Lazarovits et al. Improved isolation of extracellular vesicles by removal of both free proteins and lipoproteins eLife 2023-05-30 [PMID: 37252755]
Sara Cavallaro, Petra Hååg, Kristina Viktorsson, Anatol Krozer, Kristina Fogel, Rolf Lewensohn et al. Comparison and optimization of nanoscale extracellular vesicle imaging by scanning electron microscopy for accurate size-based profiling and morphological analysis† Nanoscale Advances 2021-06-01 [PMID: 36133670]
Luong T. H. Nguyen, Jingjing Zhang, Xilal Y. Rima, Xinyu Wang, Kwang Joo Kwak, Tamio Okimoto et al. An immunogold single extracellular vesicular RNA and protein (Au SERP) biochip to predict responses to immunotherapy in non-small cell lung cancer patients Journal of Extracellular Vesicles 2022-09-12 [PMID: 36093740]
Dmitry Ter-Ovanesyan, Maia Norman, Roey Lazarovits, Wendy Trieu, Ju-Hyun Lee, George M Church et al. Framework for rapid comparison of extracellular vesicle isolation methods eLife 2021-11-16 [PMID: 34783650]
MP Zaborowski, K Lee, YJ Na, A Sammarco, X Zhang, M Iwanicki, PS Cheah, HY Lin, M Zinter, CY Chou, G Fulci, BA Tannous, CP Lai, MJ Birrer, R Weissleder, H Lee, XO Breakefiel Methods for Systematic Identification of Membrane Proteins for Specific Capture of Cancer-Derived Extracellular Vesicles Cell Rep, 2019-04-02;27(1):255-268.e6. 2019-04-02 [PMID: 30943406] (Western Blot, Human)	Western Blot	Human

Images	Ratings	Applications	Species	Date	Details
	4 reviewed by: Verified Customer	Flow	Human	02/25/2015	View Summary Application Flow Cytometry Sample Tested See PMID 23072732 Species Human

Array MAB5048

• CD63 Antibodies
• CD63 ELISA Kit
• CD63 Lysate
• CD63 Proteins
• CD63 Proteins and Enzyme