CD45RA Antibody (1069248) [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

CD45RA is a single chain type I glycoprotein that is encoded by the human PTPRC gene.  In humans, CD45RA is one of six isoforms of the CD45 complex. These different isoforms are the result of alternative splicing and some of the other isoforms include CD45RO, CD45RB, and CD45RC. CD45RO, CD45RB, CD45RC, and CD45RA are primarily expressed on T cells. CD45RA contains exons 3, 4, and 7 but lacks both exons 5 and 6; CD45RC contains exons 3, 6, and 7. CD45RO contains exons 3 and 7 whereas CD45RB contains exons 3, 5, and 7. Both CD45RA and CD45RB are highly expressed on naïve T cells whereas CD45RO is expressed on activated and memory T cells in addition to some B cell subsets and activated monocytes. Both CD45RA and CD45RO are routinely used to characterize different subsets of Memory T cells.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Array MAB11446

• CD45RA Antibodies