CD11a/CD18 Antibody (hu1124 (Efalizumab)) [PE/Atto594] - Chimeric

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
hu1124 (Efalizumab)
Clonality
Monoclonal
Host
Rabbit
Conjugate
PE/Atto594

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Support & Research

CD11a/CD18 Antibody (hu1124 (Efalizumab)) [PE/Atto594] - Chimeric Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Efalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes.
Specificity
Binds to human LFA-1.
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Rabbit
Gene
ITGAL
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Alternate Names for CD11a/CD18 Antibody (hu1124 (Efalizumab)) [PE/Atto594] - Chimeric

  • CD11 antigen-like family member A
  • CD11a antigen
  • CD11Aantigen CD11A (p180), lymphocyte function-associated antigen 1, alphapolypeptide
  • integrin alpha-L
  • integrin gene promoter
  • integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen1; alpha polypeptide)
  • Leukocyte adhesion glycoprotein LFA-1 alpha chain
  • Leukocyte function-associated molecule 1 alpha chain
  • LFA-1 alpha
  • LFA-1
  • LFA1A
  • LFA-1A
  • lymphocyte function-associated antigen 1

Background

The CD11/18 complex of glycoproteins are dimers comprised of a common beta chain and individual alpha chains (CD11a/18 or CD11b/18 and CD11c/18). CD11a/18 is a receptor for C3bi, a complement component, CD11b/18 is Lymphocyte Function Activator, and CDD11c/18 is a lectin-like glycoprotein thought to be important for mediation of cells to other surfaces.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ITGAL