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CD11a/CD18 Antibody (hu1124 (Efalizumab)) [DyLight 488] - Chimeric

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC, B/N, CyTOF-ready
Clone
hu1124 (Efalizumab)
Clonality
Monoclonal
Host
Rabbit
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-52686AF350
Alexa Fluor 405
NBP2-52686AF405
Alexa Fluor 488
NBP2-52686AF488
Alexa Fluor 532
NBP2-52686AF532
Alexa Fluor 594
NBP2-52686AF594
Alexa Fluor 647
NBP2-52686AF647
Alexa Fluor 700
NBP2-52686AF700
Alexa Fluor 750
NBP2-52686AF750
Allophycocyanin
NBP2-52686APC
Allophycocyanin/Cy7
NBP2-52686APCCY7
DyLight 350
NBP2-52686UV
DyLight 405
NBP2-52686V
DyLight 550
NBP2-52686R
DyLight 594
NBP2-52686DL594
DyLight 650
NBP2-52686C
DyLight 680
NBP2-52686FR
DyLight 755
NBP2-52686IR
FITC
NBP2-52686F
Janelia Fluor 549
NBP2-52686JF549
Janelia Fluor 646
NBP2-52686JF646
PE
NBP2-52686PE
PE/Atto594
NBP2-52686PEATT594
PE/Cy5.5
NBP2-52686PECY55
PE/Cy7
NBP2-52686PECY7
PerCP
NBP2-52686PCP
Unconjugated
NBP2-52686-0.2mg
mFluor Violet 450 SE
NBP2-52686MFV450
mFluor Violet 500 SE
NBP2-52686MFV500
mFluor Violet 610 SE
NBP2-52686MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-52686-0.2mg
Azide and BSA Free
NBP2-52686-0.2mg
Azide and BSA Free
NBP2-52686-0.025mg
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CD11a/CD18 Antibody (hu1124 (Efalizumab)) [DyLight 488] - Chimeric Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Efalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes.
Specificity
Binds to human LFA-1.
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Rabbit
Gene
ITGAL
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Block/Neutralize
  • CyTOF-ready
  • Flow Cytometry
  • Immunohistochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Human

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CD11a/CD18 Antibody (hu1124 (Efalizumab)) [DyLight 488] - Chimeric

  • CD11 antigen-like family member A
  • CD11a antigen
  • CD11Aantigen CD11A (p180), lymphocyte function-associated antigen 1, alphapolypeptide
  • integrin alpha-L
  • integrin gene promoter
  • integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen1; alpha polypeptide)
  • Leukocyte adhesion glycoprotein LFA-1 alpha chain
  • Leukocyte function-associated molecule 1 alpha chain
  • LFA-1 alpha
  • LFA-1
  • LFA1A
  • LFA-1A
  • lymphocyte function-associated antigen 1

Background

The CD11/18 complex of glycoproteins are dimers comprised of a common beta chain and individual alpha chains (CD11a/18 or CD11b/18 and CD11c/18). CD11a/18 is a receptor for C3bi, a complement component, CD11b/18 is Lymphocyte Function Activator, and CDD11c/18 is a lectin-like glycoprotein thought to be important for mediation of cells to other surfaces.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NBP2-52686G
CD11a/CD18 Antibody (hu1124 (Efalizumab)) [DyLight 488] - Chimeric
Species: Hu
Applications: Flow, IHC, B/N, CyTOF-ready

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Bioinformatics

Gene Symbol ITGAL