CCR3 Antibody Blocking Peptide Summary
Description |
A blocking peptide containing 14 amino acids near the carboxy terminus of human CCR3. Source: Synthetic (Accession #: NP_847899) |
Source |
Synthetic |
Protein/Peptide Type |
Antibody Blocking Peptide |
Gene |
CCR3 |
Purity |
N/A |
Applications/Dilutions
Dilutions |
|
Application Notes |
This peptide is useful as a blocking peptide for NBP1-77065. For further blocking peptide related protocol, click here. |
Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles. |
Buffer |
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin. |
Preservative |
0.02% Sodium Azide |
Concentration |
0.2 mg/ml |
Purity |
N/A |
Alternate Names for CCR3 Antibody Blocking Peptide
Background
CKR3, or C-C chemokine receptor type 3, is a G protein-coupled, seven-transmembrane domain receptor protein. The chemokine eotaxin appears to be a highly specific agonist for CKR3, making CKR3 one of the factors responsible for selective recruitment of eosinophils to sites of inflammation (1). It has been shown that more than one chemokine activates CKR3, including eotaxin, RANTES, and MCP-3 (2). Since CKR3 is prominently expressed in eosinophils , it has been named the human eosinophil eotaxin receptor (2,3).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are
guaranteed for 3 months from date of receipt.
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