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CCR3 Antibody (83103)

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
83103
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
LYOPH

CCR3 Antibody (83103) Summary

Specificity
Detects mouse CCR3. Specifically stains mouse CCR3 transfectants but not the parental cell lines. Does not cross‑react with Y3 cells transfected with human CCR3.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
CCR3
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 2.5 ug/10^6 cells
Publications
Read Publications using
MAB1551 in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. See Certificate of Analysis for details.
*Small pack size (-SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for CCR3 Antibody (83103)

  • b-chemokine receptor
  • CC chemokine receptor 3
  • C-C chemokine receptor type 3
  • C-C CKR-3
  • CCR3
  • CCR-3
  • CD193 antigen
  • CD193
  • chemokine (C-C motif) receptor 3
  • CKR3CC-CKR-3CMKBR3CD193
  • eosinophil CC chemokine receptor 3
  • Eosinophil eotaxin receptor
  • MGC102841

Background

CCR3 is a G protein-linked seven transmembrane receptor that is activated by several different chemokines. It is expressed on subsets of granulocytes, monocytes, T cells and epithelial cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for CCR3 Antibody (MAB1551)(9)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 3 applications: Flow Cytometry, IHC-Fr, Neutralization.


Filter By Application
Flow Cytometry
(5)
IHC-Fr
(1)
Neutralization
(5)
All Applications
Filter By Species
Mouse
(9)
All Species
Showing Publications 1 - 9 of 9.
Publications using MAB1551 Applications Species
E Saba, YS Lee, WK Yang, YY Lee, M Kim, SM Woo, K Kim, YS Kwon, TH Kim, D Kwak, YC Park, HJ Shin, CK Han, JW Oh, YC Lee, HS Kang, MH Rhee, SH Kim Effects of a herbal formulation, KGC3P, and its individual component, nepetin, on coal fly dust-induced airway inflammation Sci Rep, 2020-08-20;10(1):14036. 2020-08-20 [PMID: 32820197] (Flow Cytometry, Mouse) Flow Cytometry Mouse
P Wang, X Qi, G Xu, J Liu, J Guo, X Li, X Ma, H Sun CCL28 promotes locomotor recovery after spinal cord injury via recruiting regulatory T cells Aging (Albany NY), 2019-09-26;11(18):7402-7415. 2019-09-26 [PMID: 31557129] (Neutralization, Mouse) Neutralization Mouse
Mosconi E, Rekima A, Seitz-Polski B Breast milk immune complexes are potent inducers of oral tolerance in neonates and prevent asthma development. Mucosal Immunol, 2010-05-19;3(5):461-74. 2010-05-19 [PMID: 20485331] (Flow Cytometry, Mouse) Flow Cytometry Mouse
Fifadara NH, Aye CC, Raghuwanshi SK, Richardson RM, Ono SJ CCR1 expression and signal transduction by murine BMMC results in secretion of TNF-alpha, TGFbeta-1 and IL-6. Int. Immunol., 2009-07-10;21(8):991-1001. 2009-07-10 [PMID: 19592420] (Flow Cytometry, Mouse) Flow Cytometry Mouse
Takeda A, Baffi JZ, Kleinman ME, Cho WG, Nozaki M, Yamada K, Kaneko H, Albuquerque RJ, Dridi S, Saito K, Raisler BJ, Budd SJ, Geisen P, Munitz A, Ambati BK, Green MG, Ishibashi T, Wright JD, Humbles AA, Gerard CJ, Ogura Y, Pan Y, Smith JR, Grisanti S, Hartnett ME, Rothenberg ME, Ambati J CCR3 is a target for age-related macular degeneration diagnosis and therapy. Nature, 2009-06-14;460(7252):225-30. 2009-06-14 [PMID: 19525930] (Neutralization, Mouse) Neutralization Mouse
Miyazaki D, Nakamura T, Ohbayashi M, Kuo CH, Komatsu N, Yakura K, Tominaga T, Inoue Y, Higashi H, Murata M, Takeda S, Fukushima A, Liu FT, Rothenberg ME, Ono SJ Ablation of type I hypersensitivity in experimental allergic conjunctivitis by eotaxin-1/CCR3 blockade. Int. Immunol., 2009-01-15;21(2):187-201. 2009-01-15 [PMID: 19147836] (IHC-Fr, Neutralization, Mouse) IHC-Fr, Neutralization Mouse
Medoff BD, Seung E, Hong S, Thomas SY, Sandall BP, Duffield JS, Kuperman DA, Erle DJ, Luster AD CD11b+ myeloid cells are the key mediators of Th2 cell homing into the airway in allergic inflammation. J. Immunol., 2009-01-01;182(1):623-35. 2009-01-01 [PMID: 19109196] (Flow Cytometry, Mouse) Flow Cytometry Mouse
Zimmermann N, McBride ML, Yamada Y, Hudson SA, Jones C, Cromie KD, Crocker PR, Rothenberg ME, Bochner BS Siglec-F antibody administration to mice selectively reduces blood and tissue eosinophils. Allergy, 2008-09-01;63(9):1156-63. 2008-09-01 [PMID: 18699932] (Flow Cytometry, Neutralization, Mouse) Flow Cytometry, Neutralization Mouse
D'Avila H, Almeida PE, Roque NR, Castro-Faria-Neto HC, Bozza PT Toll-like receptor-2-mediated C-C chemokine receptor 3 and eotaxin-driven eosinophil influx induced by Mycobacterium bovis BCG pleurisy. Infect. Immun., 2006-12-11;75(3):1507-11. 2006-12-11 [PMID: 17158890] (Neutralization, Mouse) Neutralization Mouse

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Bioinformatics

Gene Symbol CCR3
Uniprot