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CCR3 Antibody (5E8-G9-B4) [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
5E8-G9-B4
Clonality
Monoclonal
Host
Rabbit
Conjugate
Biotin

Order Details

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CCR3 Antibody (5E8-G9-B4) [Biotin] Summary

Additional Information
Recombinant Monoclonal Antibody
Immunogen
CCR3
Specificity
Recognises human CCR3, a chemokine receptor highly expressed of eosinophils, as well as Th2-Tcells, basophils, platelets, mast-cells, mononuclear phagocytes, airway epithelial cells, and hematopoietic progenitor cells (CD34+).
Isotype
IgG Kappa
Clonality
Monoclonal
Host
Rabbit
Gene
CCR3
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Alternate Names for CCR3 Antibody (5E8-G9-B4) [Biotin]

  • b-chemokine receptor
  • CC chemokine receptor 3
  • C-C chemokine receptor type 3
  • C-C CKR-3
  • CCR3
  • CCR-3
  • CD193 antigen
  • CD193
  • chemokine (C-C motif) receptor 3
  • CKR3CC-CKR-3CMKBR3CD193
  • eosinophil CC chemokine receptor 3
  • Eosinophil eotaxin receptor
  • MGC102841

Background

CKR3, or C-C chemokine receptor type 3, is a G protein-coupled, seven-transmembrane domain receptor protein. The chemokine eotaxin appears to be a highly specific agonist for CKR3, making CKR3 one of the factors responsible for selective recruitment of eosinophils to sites of inflammation (1). It has been shown that more than one chemokine activates CKR3, including eotaxin, RANTES, and MCP-3 (2). Since CKR3 is prominently expressed in eosinophils , it has been named the human eosinophil eotaxin receptor (2,3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol CCR3