CCL2/MCP1 Antibody [DyLight 650]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Rat MCP-1 (monocyte chemoattracctant protein-1) is a 148-amino acid CC chemokine with a NH2-terminal sequence of 29 residues as a signal sequence. This rat MCP-1/JE is 49-amino acid longer than human MCP-1 at 3’-end. This 3’-end is a serine and threonine rich zone, which is probably responsible for the extensive O-glycosylation. MCP-1 is produced by a wide range of cell types as a reaction to diverse inflammatory stimuli and is a chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. MCP-1 augments monocyte anti-tumor activity and has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. In atherosclerosis MCP-1 may has been implicated to be involved in the recruitment of monocytes into the arterial wall during the disease process.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Array NBP1-07035C

• CCL2/MCP1 Antibodies
• CCL2/MCP1 ELISA Kits
• CCL2/MCP1 Lysate
• CCL2/MCP1 Proteins