Caveolin-1 [p Tyr14] Antibody (750304)

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Caveolin-1 is a palmitoylated 22 kDa membrane-associated protein in caveolae, the cholesterol-rich invaginations in the plasma membrane involved in vesicular transport and regulation of lipid rafts. Caveolin-1 expression is dysregulated during cancer progression and exhibits both positive and negative effects on tumor progression. The central region of Caveolin-1 (aa 105‑125) is buried in the lipid layer, while the N- and C-terminal flanking regions are exposed to the cytoplasm and interact with many other proteins. Within these cytoplasmic regions, human Caveolin-1 shares 95% aa sequence identity with mouse and rat Caveolin-1. Alternate splicing in human, mouse and rat generates an isoform with a deletion of the N-terminal 31 residues.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Western Blot.

Showing Publication 1 - 1 of 1.

Publication using MAB7418	Applications	Species
T Tomono, K Yano, T Ogihara Snail-Induced Epithelial-to-Mesenchymal Transition Enhances P-gp-Mediated Multi Drug Resistance in HCC827 Cells J Pharm Sci, 2017-03-18;0(0):. 2017-03-18 [PMID: 28322937] (Western Blot, Human)	Western Blot	Human

Array MAB7418

• Caveolin-1 Antibodies
• Caveolin-1 ELISA Kits
• Caveolin-1 Lysate
• Caveolin-1 Proteins