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Calneuron 1 Antibody - BSA Free

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Western Blot: Calneuron 1 Antibody [NBP1-76274] - 3T3 cell lysate with CaBP8 antibody at (A) 1 and (B) 2 ug/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

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Calneuron 1 Antibody - BSA Free Summary

Immunogen
Antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human CaBP8. The immunogen is located within the first 50 amino acids of CaBP8. Amino Acid Squence: CEEPPRSQAPDFPTWEK
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CALN1
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/mL
  • Western Blot 1-2 ug/ml
Control Peptide
Calneuron 1 Peptide (NBP1-76274PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for Calneuron 1 Antibody - BSA Free

  • CABP8
  • calcium-binding protein 8
  • calcium-binding protein CABP8
  • calneuron 1
  • Calneuron I
  • calneuron-1

Background

Calcium binding proteins (CaBP) play a crucial role in the calcium-mediated cellular signal transduction pathway in the central nervous system. The CaBP family shares much similarity with CaM I (calmodulin), and it has been shown that CaBP proteins can substitute functionally for, and possibly augment the function of, CaM I. CaBP8, contains two EF-hand domains for calcium binding and shares 70% homology with CaBP7 and 50% homology with CaM I. It negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. Both CaBP8 and CaBP7 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca2+-sensing by these family members.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CALN1
Uniprot