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C5L2/GPR77 Antibody

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Western Blot: C5L2/GPR77 Antibody [NBP3-10864] - Western blot analysis of C5L2/GPR77 in Human 786-0 Whole Cell lysates. Antibody dilution at 1ug/ml

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

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C5L2/GPR77 Antibody Summary

Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human C5L2/GPR77 (NP_001258678.1). Peptide sequence ALAHSCLNPMLFLYFGRAQLRRSLPAACHWALRESQGQDESVDSKKSTSH
Clonality
Polyclonal
Host
Rabbit
Gene
C5AR2
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1.0 ug/ml
Theoretical MW
37 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS, 2% Sucrose
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Affinity purified

Alternate Names for C5L2/GPR77 Antibody

  • C5a anaphylatoxin chemotactic receptor C5L2
  • C5L2
  • C5L2G-protein coupled receptor 77
  • G protein-coupled receptor 77
  • G protein-coupled receptor C5L2
  • GPF77
  • GPR77

Background

Official Gene Symbol: GPR77 Gen Bank Accession Number: NP_060955 Gene ID: 27202 (human) Gene Map Locus: 19q13.33 (human) C5L2 is 337A.A orphan member that belongs to anaphylatoxin receptor family. It is a seven transmembrane G-protein-coupled receptor consisting of an N-terminal N-glycosylation site, several conserved cysteines and several potential C-terminal phosphorylation sites. It binds to C5a and C5a-des-Arg and serves as a highly regulated scavenger receptor with a negative modulatory influence on C5aR-mediated inflammation. Northern Blot analysis suggests it is co- expressed along with C5aR in different tissues and cells including neutrophils/macrophages, mast cells, dendritic cells, brain, lung, heart, kidney, liver, ovary and testis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol C5AR2