BST2 Antibody - Azide Free Summary
Immunogen |
A portion of amino acids 80-130 of human BST2 was used as the immunogen for this antibody. |
Predicted Species |
Orangutan (100%), Chimpanzee (100%), Rhesus Macaque (94%). Backed by our 100% Guarantee. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
BST2 |
Purity |
Protein A purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Flow Cytometry reported in scientific literature (Crother et al (2011); PMID 21695198)
- Immunohistochemistry
- Immunohistochemistry-Paraffin 5 ug/ml
- Simple Western 1:200
- Western Blot 2-4 ug/ml
|
Application Notes |
BST2 is a 180 amino acid protein with an observed molecular weight of approximately 30 kDa in western blotting (see Ishikawa et all, 1995 PMID 7607676). In Simple Western only 10-15 uL of the recommended dilution is used per data point. |
Reactivity Notes
The BST2 amino acid sequence used as immunogen for this antibody is 100% homologous in White-cheeked Gibbon, Great Ape, and Gibbon.
Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles. |
Buffer |
PBS |
Preservative |
No Preservative |
Concentration |
1.0 mg/ml |
Purity |
Protein A purified |
Alternate Names for BST2 Antibody - Azide Free
Background
BST2, also known as CD317, HM1.24 antigen, DAMP-2 and recently designated tetherin, is an integral membrane protein with a novel topology. The specific function of the BST2, encoded by the bone marrow stromal cell antigen 2 gene, is undetermined; however, it may play a role in pre-B-cell growth, rheumatoid arthritis, and in antiretroviral defense, that blocks release of retrovirus from the cell surface. BST2 is highly expressed during B-cell development, from pro-B precursors to plasma cells, T-cells, monocytes, Nk cells and DCs (at protein level).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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