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beta-Galactosidase-1/GLB1 Antibody

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Immunohistochemistry-Paraffin: beta-Galactosidase-1/GLB1 Antibody [NBP2-49602] - Staining in human epididymis and skeletal muscle tissues using anti-GLB1 antibody. Corresponding GLB1 RNA-seq data are presented for the same tissues.
Orthogonal Strategies: Immunohistochemistry-Paraffin: beta-Galactosidase-1/GLB1 Antibody [NBP2-49602] - Staining in human epididymis and skeletal muscle tissues using anti-GLB1 antibody. Corresponding GLB1 ...read more
Immunohistochemistry-Paraffin: beta-Galactosidase-1/GLB1 Antibody [NBP2-49602] - Staining of human skeletal muscle shows low expression as expected.
Immunohistochemistry-Paraffin: beta-Galactosidase-1/GLB1 Antibody [NBP2-49602] - Staining of human epididymis shows high expression.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

  

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beta-Galactosidase-1/GLB1 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: GRYWPARGPQLTLFVPQHILMTSAPNTITVLELEWAPCSSDDPELCAVTFVDRPVIGSSVTYDHPSKPVEKRLMPPPPQKNKDSWLDHV
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GLB1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
beta-Galactosidase-1/GLB1 Recombinant Protein Antigen (NBP2-49602PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for beta-Galactosidase-1/GLB1 Antibody

  • Acid beta-galactosidase
  • beta-galactosidase
  • betaGalactosidase1
  • beta-Galactosidase-1
  • EBP
  • EC 3.2.1.23
  • elastin receptor 1 (67kD)
  • Elastin receptor 1
  • elastin receptor 1, 67kDa
  • ELNR1
  • galactosidase, beta 1
  • GLB1
  • Lactase
  • MPS4B

Background

The GLB1 gene encodes beta-galactosidase-1 (EC 3.2.1.23), a lysosomal hydrolase that cleaves the terminal beta-galactose from ganglioside substrates and other glycoconjugates (Yoshida et al., 1991 [PubMed 1907800]). Beta-galactosidase also occurs in a complex with neuraminidase (NEU1; MIM 608272) and protective protein/cathepsin A (PPCA; MIM 256540), which is a component of certain cell surface receptors (Hinek, 1996 [PubMed 8922281]). See also galactosylceramidase (GALC; MIM 606890) (EC 3.2.1.46), a genetically distinct beta-galactosidase that is involved in the catabolism of other lipid compounds.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol GLB1