The GLB1 gene encodes beta-galactosidase-1 (EC 3.2.1.23), a lysosomal hydrolase that cleaves the terminal beta-galactose from ganglioside substrates and other glycoconjugates (Yoshida et al., 1991 [PubMed 1907800]). Beta-galactosidase also occurs in a complex with neuraminidase (NEU1; MIM 608272) and protective protein/cathepsin A (PPCA; MIM 256540), which is a component of certain cell surface receptors (Hinek, 1996 [PubMed 8922281]). See also galactosylceramidase (GALC; MIM 606890) (EC 3.2.1.46), a genetically distinct beta-galactosidase that is involved in the catabolism of other lipid compounds.[supplied by OMIM]
![Western Blot beta-Galactosidase-1/GLB1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/beta-Galactosidase-1_AF6464_Western_Blot_11762.jpg)
![Simple Western beta-Galactosidase-1/GLB1 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/betaGalactosidase1_AF6464_Simple_Western_17025.jpg)
![Enzyme Activity beta-Galactosidase-1/GLB1 [Unconjugated]](http://images.novusbio.com/fullsize2/6464-gh_recombinant-human-beta-galactosidase-1-glb1-protein-cf-enzyme-activity-2022023152944.jpg)
![Enzyme Activity beta-Galactosidase-1/GLB1 [Unconjugated]](http://images.novusbio.com/fullsize2/6464-gh_recombinant-human-beta-galactosidase-1-glb1-protein-cf-2022023153630.jpg)
![SDS-PAGE beta-Galactosidase-1/GLB1 [Unconjugated]](http://images.novusbio.com/fullsize2/6464-gh_recombinant-human-beta-galactosidase-1-glb1-protein-cf-sds-page-2022023154159.jpg)