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beta-2 Adrenergic R/ADRB2 Antibody (586107) [PE/Cy5.5]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
586107
Clonality
Monoclonal
Host
Mouse
Conjugate
PE/Cy5.5

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB100401U-100UG
Alexa Fluor 405
FAB100401V-100UG
Alexa Fluor 488
FAB100401G-100UG
Alexa Fluor 532
FAB100401X
Alexa Fluor 594
FAB100401T-100UG
Alexa Fluor 647
FAB100401R-100UG
Alexa Fluor 700
FAB100401N-100UG
Alexa Fluor 750
FAB100401S-100UG
Allophycocyanin
FAB100401A
Allophycocyanin/Cy7
FAB100401APCCY7
Biotin
FAB100401B
CoraFluor 1
FAB100401CL1
DyLight 350
FAB100401D
DyLight 405
FAB100401E
DyLight 488
FAB100401K
DyLight 550
FAB100401L
DyLight 594
FAB100401M
DyLight 650
FAB100401W
DyLight 680
FAB100401Y
DyLight 755
FAB100401Z
FITC
FAB100401F
HRP
FAB100401H
Janelia Fluor 525
FAB100401JF525
Janelia Fluor 549
FAB100401I
Janelia Fluor 585
FAB100401JF585
Janelia Fluor 635
FAB100401JF635
Janelia Fluor 646
FAB100401J
Janelia Fluor 669
FAB100401JF669
PE
FAB100401P
PE/Atto594
FAB100401PEATT594
PE/Cy7
FAB100401PECY7
PerCP
FAB100401C
Unconjugated
MAB100401-100
mFluor Violet 450 SE
FAB100401MFV450
mFluor Violet 500 SE
FAB100401MFV500
mFluor Violet 610 SE
FAB100401MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB100401-100
Carrier Free
MAB100401-100
Carrier Free
MAB100401-SP
Carrier Free
FAB100401V-100UG
Carrier Free
FAB100401U-100UG
Carrier Free
FAB100401T-100UG
Carrier Free
FAB100401S-100UG
Carrier Free
FAB100401R-100UG
Carrier Free
FAB100401N-100UG
Carrier Free
FAB100401G-100UG
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beta-2 Adrenergic R/ADRB2 Antibody (586107) [PE/Cy5.5] Summary

Immunogen
NS0 mouse myeloma cell line transfected with human beta ‑2 Adrenergic R/ADRB2
Accession # P07550
Specificity
Detects human beta ‑2 Adrenergic R/ADRB2 in direct ELISAs.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Alternate Names for beta-2 Adrenergic R/ADRB2 Antibody (586107) [PE/Cy5.5]

  • ADRB2
  • ADRB2R
  • ADRBR
  • adrenergic, beta-2-, receptor, surface
  • B2AR
  • B2ARADRB2R
  • BAR
  • beta-2 Adrenergic R
  • beta-2 adrenergic receptor
  • beta2 AdrenergicR
  • beta-2 AdrenergicR
  • Beta-2 adrenoceptor
  • Beta-2 adrenoreceptor
  • BETA2AR
  • catecholamine receptor

Background

The beta-2 adrenoceptor (ADRB2) is an Adrenergic Receptor expressed in smooth muscle and metabolic tissues. Activation of this receptor induces a decrease in gastrointestinal motility, bronchodilation, vasodilation in skeletal and cardiac muscle, and glycogenolysis in liver. The beta-2 adrenoceptor is also a major lipolytic receptor in human fat cells and may be involved in obesity. Agonists of ADRB2 are most widely used for the treatment of asthma. In complex with beta-arrestin-1 and c-src, the beta-2 adrenergic receptor activates MAP kinases ERK1(MAPK3) and ERK2 (MAPK1). Expression of the beta-2 adrenoceptor has been reported in adipose, blood, brain, heart, lung, nose, pancreas, skeletal muscle, skin, and vessel. ESTs have been isolated from breast, liver, liver/spleen, placenta, and uterus libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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beta-2 Adrenergic
R/ADRB2 Antibody (586 ...
FAB100401PECY55
beta-2 Adrenergic R/ADRB2 Antibody (586107) [PE/Cy5.5]
Species: Hu
Applications: Flow

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