B7-1/CD80 Antibody (62N3G8) - BSA Free

The CD80 antigen (B7-1, BB1) recognizes a 60-kD transmembrane glycoprotein that is a member of the immunoglobulin family. This molecule shares with CD86 the capability to be the ligand for two structurally similar molecules expressed on T lymphocytes, CD28 and CD152 (CTLA-4). CD80 antigen is expressed on in vitro activated B lymphocytes after 24h stimulation and at maximal level 48-72h post activation. It is not expressed on the majority of resting B cells from peripheral blood but identifies a subpopulation of B cells that has been previously activated. The antigen is also expressed by HTLV-1 transformed T cells activated monocytes, and constitutively on dendritic cells. CD80 binding provides costimulatory signals for T cell activation.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 2 applications: IHC-P, WB.

Showing Publications 1 - 4 of 4.

Publications using NBP2-25255	Applications	Species
Wu J, Jing X, Du Q et al. Disruption of the Clock Component Bmal1 in Mice Promotes Cancer Metastasis through the PAI-1-TGF-?-myoCAF-Dependent Mechanism Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023-06-17 [PMID: 37330661] (IHC-P, Mouse) Details: IHC-P: antibdy dilution: 1:200. Antigen retrieval: citrate-based solution pH 6.0 (H-3300, Vector)	IHC-P	Mouse
PokrYvkovA B, SmahelovA J, DalewskA N et al. ARG1 mRNA Level Is a Promising Prognostic Marker in Head and Neck Squamous Cell Carcinomas Diagnostics (Basel, Switzerland) 2021-03-31 [PMID: 33807310]
Zhao Y Lee CK Lin CH et al. PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways Immunity 2019-12-17 [PMID: 31757674] (WB, Human)	WB	Human
Herrera M, Soderberg M, Sabirsh A et al. Inhibition of T-cell activation by CTLA4-Fc is sufficient to ameliorate proteinuric kidney disease Am. J. Physiol. Renal Physiol. 2016-07-20 [PMID: 27440778]

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Verified Customer	WB	Human	06/28/2018	View Summary Application Western Blot Sample Tested Raji whole cell lysate Species Human Lot AB021845613G801
Enlarge	5 reviewed by: Verified Customer	Flow	Human	06/28/2018	View Summary Application Flow Cytometry Sample Tested Raji lymphoma cells Species Human Lot AB021845613G801

Array NBP2-25255

• B7-1/CD80 Antibodies
• B7-1/CD80 ELISA Kit
• B7-1/CD80 Proteins
• B7-1/CD80 Proteins and Enzymes
• B7-1/CD80 ELISAs