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Ataxin-3 Antibody (7B2I1)

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Western Blot: Ataxin-3 Antibody (7B2I1) [NBP3-33328] - Western blot analysis of lysates from various lysates, using Ataxin-3Rabbit mAb at 1:2000 dilution.Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at ...read more

Product Details

Summary
Reactivity Mu, RtSpecies Glossary
Applications WB, ELISA
Clone
7B2I1
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Ataxin-3 Antibody (7B2I1) Summary

Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 190-361 of human Ataxin-3 (ATXN3) (NP_004984.2).

Sequence:
KLIGEELAQLKEQRVHKTDLERVLEANDGSGMLDEDEEDLQRALALSRQEIDMEDEEADLRRAIQLSMQGSSRNISQDMTQTSGTNLTSEELRKRREAYFEKQQQKQQQQQQQQQQGDLSGQSSHPCERPATSSGALGSDLGDAMSEEDMLQAAVTMSLETVRNDLKTEGKK
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
ATXN3
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA Recommended starting concentration is 1 ug/mL
  • Western Blot 1:1000 - 1:5000
Theoretical MW
41 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 50% glycerol, 0.05% BSA
Preservative
0.05% Proclin 300
Purity
Affinity purified

Alternate Names for Ataxin-3 Antibody (7B2I1)

  • AT3
  • ataxin 3
  • Ataxin3
  • Ataxin-3
  • ATX3AT3
  • ATXN3
  • EC 3.4.19.12
  • EC 3.4.22
  • JOS
  • Machado-Joseph disease protein 1
  • MJD1
  • MJDolivopontocerebellar ataxia3, autosomal dominant, ataxin 3)
  • olivopontocerebellar ataxia 3
  • SCA3
  • Spinocerebellar ataxia type 3 protein

Background

Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol ATXN3