ARF1,2,3,4 Antibody

DP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family. The family members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking as activators of phospholipase D. The gene products, including 6 ARF proteins and 11 ARF-like proteins, constitute a family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2 and ARF3), class II (ARF4 and ARF5) and class III (ARF6), and members of each class share a common gene organization. The ARF1 protein is localized to the Golgi apparatus and has a central role in intra-Golgi transport. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 2 of 2.

Publications using NB100-55421	Applications	Species
Klein S, Partisani M, Franco M et al. EFA6 Facilitates the Assembly of the Tight Junction by Coordinating an Arf6-dependent -independent Pathway. J Biol Chem;283(44):30129-30138. 2008-01-01 [PMID: 18779331]
Dubois T, Paleotti O, Mironov AA et al. Golgi-localized GAP for Cdc42 functions downstream of ARF1 to control Arp2/3 complex and F-actin dynamics. Nat Cell Biol 2005-04-01 [PMID: 15793564]

Array NB100-55421

• ARF1,2,3,4 Antibody