Recombinant Human Aprataxin His Protein

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SDS-Page: Aprataxin Protein [NBP1-40397] - Aprataxin, 23.9kDa (205aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
0.25 mg/ml

Order Details

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Recombinant Human Aprataxin His Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-168 of Human Aprataxin

Source: E.coli

Amino Acid Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWAGSMQD PKMQVYKDEQ VVVIKDKYPK ARYHWLVLPW TSISSLKAVA REHLELLKHM HTVGEKVIVD FAGSSKLRFR LGYHAIPSMS HVHLHVISQD FDSPCLKNKK HWNSFNTEYF LESQAVIEMV QEAGRVTVRD GMPELLKLPL RCHECQQLLP SIPQLKEHLR KHWTQ

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
APTX
Purity
>95%, by SDS-PAGE

Applications/Dilutions

Dilutions
  • SDS-Page
Theoretical MW
23.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20 mM Tris-HCl buffer (pH7.5), 20% glycerol, 100 mM NaCl, 0.1 mM PMSF
Preservative
No Preservative
Concentration
0.25 mg/ml
Purity
>95%, by SDS-PAGE

Alternate Names for Recombinant Human Aprataxin His Protein

  • AOA1EAOH
  • AOAMGC1072
  • aprataxin
  • ataxia 1, early onset with hypoalbuminemia
  • AXA1
  • EC 3.-
  • EOAHA
  • FHA-HIT
  • FLJ20157
  • Forkhead-associated domain histidine triad-like protein

Background

Aprataxin is a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. Aprataxin may play a role in single-stranded DNA repair. Mutations in the gene have been associated with neurological disorder known as ataxia oculomotor apraxia-1. Recombinant Aprataxin protein was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol APTX